Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

Part of paid clinical trials in Aurora, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT05896579
Status
Recruiting
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Conditions

  • COPD
  • Exercise
  • Exercise Training
  • Pulmonary Hypertension
  • Right Ventricular Dysfunction

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Exercise — BEHAVIORAL
    After a brief warmup, participants will be asked to perform approximately 5 minutes of exercise at moderate intensity and then approximately 2 minutes of exercise at high intensity.

Study Details

This study plans to learn about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during rest and moderate- vs high-intensity exercise. By identifying patterns of right ventricular dysfunction, this study will help identify better treatments for patients with COPD in the future.

Key Dates

Start date
Aug 22, 2023
Status verified
May 2026
Primary completion
May 31, 2030
Completion
Aug 31, 2030

Study Design

Enrollment
60 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: COPD
    Participants will complete testing at rest and during moderate- and high-intensity exercise to identify patterns of right ventricular responses.

Primary Outcome Measure

Right ventricular contractility measured by transthoracic echocardiography [ Time Frame: Up to 1 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Colorado Anschutz Medical CampusAuroraColorado80045
Lindsay Forbes, MD
[email protected]
303-724-4020

Find similar trials in Aurora, CO

By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Colorado Anschutz Medical Campus· Aurora, CO

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