Hypoxia and Heart Rate Variability

Part of paid clinical trials in Miami, Florida.

Sponsor
University of Miami
Study ID
NCT05606406
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Nocturnal Oxygen — OTHER
    Nocturnal oxygen will be increased hourly for a period of four hours up to 4 liters per minute (LPM). If the oxygen saturation (SpO2) falls below 70% the oxygen rate will be increased until patients achieve the threshold of 70% and then will proceed with titrations of 1 liter per minute LPM per hour.

Study Details

The purpose of this study is to evaluate how variations in oxygen demands may change heart electrical activity in individuals with and without oxygen dependence.

Key Dates

Start date
May 30, 2026
Status verified
Feb 2026
Primary completion
Dec 30, 2027
Completion
Dec 30, 2027

Study Design

Enrollment
70 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Healthy Control Group
    Individuals without lung disease will receive oxygen for a period of four hours
  • Active Comparator: Nocturnal hypoxemia group
    Individuals with lung disease will receive oxygen for a period of four hours

Primary Outcome Measure

QT Variability Index [ Time Frame: Up to 10 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MiamiMiamiFlorida33136
Trishul Siddharthan, MD
[email protected]
305-243-6388
Trishul Siddharthan, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Miami, FL

By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Miami· Miami, FL

Related Studies