Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

Part of paid clinical trials in Lexington, Kentucky.

Sponsor
Gopalkumar Rakesh
Study ID
NCT05295953
Status
Completed

Conditions

  • Hiv
  • Tobacco Smoking

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • TBS — DEVICE
    Four sessions of TBS at 120 % resting motor threshold, delivered using MagVenture B65 A/P coil, each lasting 10 minutes and separated by 50 minutes intervals. Targeting will be done using neuronavigation and processed resting state brain scan.
  • Sham TMS — DEVICE
    Four sessions of sham TMS delivered using MagVenture B65 A/P coil.

Study Details

To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation. We hypothesize 4 sessions of TBS to the left DLPFC will significantly improve attentional bias and craving for smoking cues compared to neutral cues in a population of subjects who are smokers with HIV/AIDS compared to sham stimulation.

Key Dates

Start date
Apr 1, 2022
Status verified
Oct 2025
Primary completion
Jul 31, 2024
Completion
Jul 31, 2024

Study Design

Enrollment
4 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: TBS (Theta burst stimulation)
    Four sessions of TBS in one day
  • Placebo Comparator: Sham TMS
    Four sessions of sham TMS

Primary Outcome Measure

Gaze Fixation on Smoking Cues [ Time Frame: On Day 1 of the study ]

Locations (2)

FacilityCityStateZIPSite coordinators
245 Fountain CourtLexingtonKentucky40513-
University of KentuckyLexingtonKentucky40513-

Find similar trials in Lexington, KY

By condition
HIV
By specialty
Infectious disease
By research site
245 Fountain Court· Lexington, KYUniversity of Kentucky· Lexington, KY

Related Studies