Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Boston Children's Hospital
Study ID
NCT05241418
Status
Recruiting
Apply to this trial

Conditions

  • Congenital Heart Disease
  • Fibrosis Myocardial
  • Fibrosis; Heart

Eligibility Criteria

Sex
ALL
Age
13 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Atrial 3D late gadolinium enhancement — DIAGNOSTIC_TEST
    We will use cardiac MRI to take a picture of the atria. This picture will be used to identify scar tissue within the atria.

Study Details

In this research study the investigators want to learn more about how well the investigators can visualize scar tissue in the heart by MRI. In patients with congenital heart disease who need a procedure in the electrophysiology laboratory, how the MRI findings match the findings in the electrophysiology laboratory is not known. This study works to answer these questions. Participants will undergo a cardiac MRI as part of the routine clinical care that was ordered by their doctors and additional imaging by cardiac MRI will be performed.

Key Dates

Start date
Mar 23, 2022
Status verified
Feb 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2029

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Patients with congenital heart disease undergoing a cardiac MRI with Gadolinium
    Patients with congenital heart disease who are undergoing a clinically-ordered cardiac MRI and as part of that MRI the contrast agent, Gadolinium, will be administered.

Primary Outcome Measure

Total atrial fibrosis content from 3D-LGE-CMR [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02130
Daniel A Castellanos, MD
[email protected]
6173557769
Edward O'Leary, MD
[email protected]
6173557275

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By research site
Boston Children's Hospital· Boston, MA

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