Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Sophia Koutsogiannaki
Study ID
NCT04296071
Status
Recruiting
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Conditions

  • Cardiopulmonary Bypass
  • Lung Injury

Eligibility Criteria

Sex
ALL
Age
N/A - 12 Months
Healthy Volunteers
Not accepted

Interventions

  • Research study — OTHER
    Blood and tracheal aspirates will be collected

Study Details

Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.

Key Dates

Start date
Oct 14, 2022
Status verified
May 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
56 participants (estimated)

Arms

  • Arm: Group 1
    patients who tend to have longer CPB
  • Arm: Group 2
    Patients who have shorter CPB

Primary Outcome Measure

Perform neutrophil analysis in blood and tracheal aspirates samples [ Time Frame: 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02115
Rachel Bernier

Find similar trials in Boston, MA

By research site
Boston Children's Hospital· Boston, MA

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