Sleep-dependent Learning in Aging

Part of paid clinical trials in Amherst, Massachusetts.

Sponsor
University of Massachusetts, Amherst
Study ID
NCT03840083
Status
Recruiting

Conditions

  • Sleep

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • Sleep — BEHAVIORAL
    Participants will sleep (either a mid-day nap or normal overnight sleep)

Study Details

The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.

Key Dates

Start date
Jul 15, 2018
Status verified
Mar 2025
Primary completion
Jul 14, 2025
Completion
Jul 15, 2025

Study Design

Enrollment
584 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Sleep
    Individuals will either nap (Exps 1, 4) or have overnight sleep (Exps 2, 3, 5, 6)
  • No Intervention: Wake
    Individuals will stay awake for the same amount of time as they slept in the sleep condition

Primary Outcome Measure

Change in memory accuracy for intervention compared to control [ Time Frame: 2 hours (Experiments 1,4) or 12 hours (Experiments 2,3,5,6) ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of MassachusettsAmherstMassachusetts01003
Mary Emma Searles
413-545-4831

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