The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Beth Israel Deaconess Medical Center
Study ID
NCT03767426
Status
Recruiting
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Conditions

  • Sleep
  • Sleep Deprivation

Eligibility Criteria

Sex
ALL
Age
18 Years - 35 Years
Healthy Volunteers
Accepted

Interventions

  • Sleep Deprivation — BEHAVIORAL
    Subjects are sleep deprived for an entire night
  • Daytime nap — BEHAVIORAL
    After a night of sleep deprivation, participants will be given a 2 hour nap opportunity

Study Details

To further understand the impact of acute sleep deprivation and recovery sleep on the processing of emotional information the investigators will address and attempt to answer three questions, (i) how both undisturbed sleep and sleep deprivation affect the processing and retrieval of emotional information, (ii) what neural and psychophysiological mechanisms are associated with these behavioral effects, and (iii) to explore the ability of recovery sleep to reverse the effects of sleep deprivation. Together, these studies will provide a greater breadth and depth of knowledge concerning sleep's role in emotion processing and regulation. Given the growing societal tendency to view sleep as unproductive-foregoing it to lengthen work days and increase social opportunities- such knowledge would be of practical importance for understanding the role of sleep in healthy emotional functioning, particular for individuals experiencing periods of increased stress and emotional distress (e.g., new parents, hospital staff, or combat troops).

Key Dates

Start date
Mar 1, 2019
Status verified
Aug 2024
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • No Intervention: Overnight sleep
    Subjects are permitted a night of polysomnograph-recorded sleep before participating in training and testing sessions the next day
  • Active Comparator: Sleep deprivation
    Subjects sleep deprived before participating in training and testing sessions the next day
  • Experimental: Daytime Nap
    Subjects are trained and then retested after a daytime nap

Primary Outcome Measure

Morphed Face Accuracy and Intensity [ Time Frame: 1-24 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Tony CunninghamBostonMassachusetts02215
Tony Cunningham, PhD
[email protected]
617-632-7927
Robert Stickgold, PhD
[email protected]
617-233-3768
Robert Stickgold, PhD (SUB_INVESTIGATOR)

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