Exercise Intolerance in Heart Failure

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT03775577
Status
Recruiting
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Conditions

  • Heart Failure With Normal Ejection Fraction

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Accepted

Study Details

The investigators are studying whether metabolic abnormalities in cardiac and skeletal muscle in patients with heart failure with preserved ejection fraction (HFpEF) are associated with debilitating exercise intolerance.

Key Dates

Start date
Apr 1, 2017
Status verified
Mar 2026
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
130 participants (estimated)

Arms

  • Arm: HFpEF
    Participants with Heart Failure with Preserved Ejection Fraction
  • Arm: HFrEF
    Participants with Heart Failure with Reduced Ejection Fraction
  • Arm: Hypertensive Subjects
    Participants with Hypertension
  • Arm: Healthy Subjects
    Participants without heart failure and without commodities

Primary Outcome Measure

Skeletal muscle mitochondrial function [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins HospitalBaltimoreMaryland21287
Tricia Steinberg, MSN
[email protected]
443-287-3469

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By research site
Johns Hopkins Hospital· Baltimore, MD

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