Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome

Part of paid clinical trials in Cincinnati, Ohio.

Sponsor
Children's Hospital Medical Center, Cincinnati
Study ID
NCT01902407
Status
Enrolling By Invitation

Conditions

  • Down Syndrome
  • Obstructive Sleep Apnea

Eligibility Criteria

Sex
ALL
Age
1 Year - 90 Years
Healthy Volunteers
Not accepted

Study Details

The purpose of this research study is to develop a way of predicting with computers how surgery on the airway will affect night time breathing called Obstructive Sleep Apnea (OSA) in children with Down Syndrome. A research measurement for airway resistance will also be done during the clinical sleep MRI. The airway resistance measurement will take about 10 minutes and is done during sleep. The airway resistance measurement is called critical closing pressure (Pcrit).

Key Dates

Start date
Mar 31, 2011
Status verified
Apr 2025
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
73 participants (estimated)

Arms

  • Arm: Diagnostic MRI and CT scan of the airway
    All patients seen at CCHMC (up to 90 years of age) who are scheduled to have a clinical sleep MRI or CT scan for their OSA airway or lung disease. Scheduled for both Sleep diagnostic tests (Sleep MRI and CT scans).

Primary Outcome Measure

Measurement of critical closing pressure of the airway-Sleep MRI [ Time Frame: Day 1 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Cincinnati Children's Hospital Medical CenterCincinnatiOhio45229-

Find similar trials in Cincinnati, OH

By research site
Cincinnati Children's Hospital Medical Center· Cincinnati, OH

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