Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Arunark Kolipaka
Study ID
NCT01757730
Status
Recruiting
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Conditions

  • Aortic Aneurysms
  • Cardiac Transplant Rejection
  • Heart Failure
  • Liver Fibrosis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging technique a person is laid in an MR scanner and a paddle (plastic drum) is put on the area of interest to send sound vibration via a speaker placed outside the scan room which is connecting plastic drum via a plastic tube. These vibrations are scanned using MRI to estimate the stiffness of soft tissues such as liver, heart, kidneys, breast etc.

Key Dates

Start date
Mar 31, 2012
Status verified
Apr 2025
Primary completion
Mar 1, 2028
Completion
Mar 1, 2028

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: Altered Stiffness
    Tissue stiffness will be evaluated in subjects those with disease conditions where stiffness changes from normal. These studies will be repeated for reproducibility.
  • Arm: Healthy Volunteers
    Tissue stiffness will be evaluated in normal subjects to determine the normal values. These studies will be repeated for reproducibility.

Primary Outcome Measure

Stiffness of soft tissues [ Time Frame: Participants will be followed for the duration of hospital stay, ecah clinical visit after discharge for an expected average up to 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The Ohio State University Wexner Medical CenterColumbusOhio43210
Kristin L Thompson, B.S.
[email protected]
614-366-5429
Arunark Kolipaka, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Columbus, OH

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
The Ohio State University Wexner Medical Center· Columbus, OH

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