Impact of Roflumilast on Visceral Adiposity and Metabolic Profile in Chronic Obstructive Pulmonary Disease
- Sponsor
- Laval University
- Study ID
- NCT01701934
- Phase
- PHASE2
- Status
- Terminated
Conditions
- Chronic Obstructive Pulmonary Disease
- Metabolic Syndrome
Eligibility Criteria
- Sex
- MALE
- Age
- 40 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Roflumilast — DRUG500 mcg, oral, once daily for 6 months
- Placebo — DRUGOne placebo pill daily, for 6 months
Study Details
The purpose of this study is to determine whether roflumilast can improve metabolic profile and reduce visceral adiposity in patients with chronic obstructive pulmonary disease (COPD).
Key Dates
- Start date
- Feb 28, 2013
- Status verified
- Nov 2014
- Primary completion
- Oct 31, 2014
- Completion
- Dec 31, 2014
Study Design
- Enrollment
- 14 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: RoflumilastRoflumilast 500 mcg, once daily for 6 months
- Placebo Comparator: Placebo pillPlacebo pill, once daily for 6 months
Primary Outcome Measure
Change in intrabdominal adiposity [ Time Frame: At baseline and 6 months later ]
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