Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Brigham and Women's Hospital
Study ID
NCT01177618
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.

Key Dates

Start date
Jul 31, 1994
Status verified
Oct 2025
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Probands
    Severe, early-onset COPD subjects that bring the family into the study
  • Arm: Relatives
    Relatives of early-onset COPD probands, including first-degree relatives (parents, siblings, and children), second-degree relatives (aunts, uncles, grandparents, half-siblings), spouses, and other affected individuals.

Primary Outcome Measure

No Primary Outcome [ Time Frame: Single Visit for approximately two hours to collect study data and samples ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Brigham and Women's HospitalBostonMassachusetts02115
Edwin Silverman
[email protected]
617-525-0856
Violet Richardson
[email protected]
617-525-2128
Edwin K. Silverman, M.D., Ph.D. (PRINCIPAL_INVESTIGATOR)
Dawn L. DeMeo, M.D. (SUB_INVESTIGATOR)
Craig P. Hersh, M.D. (SUB_INVESTIGATOR)
Michael H. Cho, M.D. (SUB_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
COPD
By specialty
PulmonologyLung disease
By research site
Brigham and Women's Hospital· Boston, MA

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