Jacksonville, FL Clinical Trials Report — April 2026

For Jacksonville residents considering participation in clinical research, April 2026 presents a critical window to join studies before enrollment concludes. Across the city, 54 clinical trials are slated to close within the next 90 days. This urgency is particularly relevant for healthy volunteers, as 7 of these rapidly closing studies are still actively seeking participants without specific health conditions. Individuals interested in contributing to medical advancements should explore these options promptly.

New Opportunities for Weight Management and More

This month brings several high-profile new trials to Jacksonville, FL, including significant Phase 3 studies from major sponsors. These trials offer participants the chance to engage with cutting-edge treatments and diagnostic approaches across a range of health challenges.

• Novo Nordisk A/S is sponsoring NCT07533175, "AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight." This Phase 3 study, aiming for 630 participants, investigates if NNC0487-0111 is safe and effective for treating individuals with excess body weight and type 2 diabetes. Participants will receive weekly injections of either NNC0487-0111 or another study treatment.
• Also from Novo Nordisk A/S is NCT07509307, "AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain." This Phase 3 study, designed for 400 participants, will compare the safety and effect of NNC0487-0111 against a placebo in people with excess body weight and knee osteoarthritis, administered as a weekly injection.
• Mayo Clinic is leading NCT07525323, "EMG ss AMG In Robotic/Laparoscopic Surgery." This study, aiming for 400 participants, seeks to compare the amount of rocuronium administered during robotic or laparoscopic surgery when using different monitoring techniques (acceleromyography versus electromyography).
• Mead Johnson Nutrition is sponsoring NCT07513506, "Extensively Hydrolyzed Formula Growth Monitioring Study (GMS)." This research study, involving 214 participants, compares an investigational infant formula against a currently marketed infant formula to evaluate growth outcomes.

This month, Jacksonville saw the opening of 7 new clinical trials, a decrease from the 12 trials that launched in March 2026. Despite this dip in new openings, the city continues to be a hub for medical research, with a total of 865 clinical trials currently recruiting across 306 research facilities.

Opportunities for Healthy Volunteers and Diverse Participants

For individuals without a specific medical condition, there are significant opportunities to contribute. 2 of the 7 new trials launched this month are actively seeking healthy volunteers. Across Jacksonville, a total of 57 clinical trials are currently recruiting healthy participants, providing numerous avenues for those interested in supporting medical research.

Participation in clinical trials is open to a diverse range of individuals. Of the new trials launched this month, 1 includes children and 6 include older adults, ensuring that various age groups have opportunities to contribute to medical science. New trials this month are exploring a range of conditions, including overweight, obesity, growth, osteoarthritis of the knee, spontaneous coronary artery dissection, and diabetes mellitus. The majority of new studies are categorized as "OTHER" (3 trials) or "DRUG" (2 trials), with one behavioral and one device trial also opening.

Jacksonville's Leading Research Facilities

Jacksonville is home to several prominent research institutions that consistently run a high volume of clinical trials. These facilities are key destinations for individuals seeking to participate in medical research:

• Mayo Clinic in Florida (157 trials)
• Mayo Clinic (67 trials)
• Mayo Clinic Florida (61 trials)
• Mayo Clinic Jacksonville (43 trials)
• Research Site (41 trials)
• Nemours Children's Clinic-Jacksonville (31 trials)
• Baptist MD Anderson Cancer Center (21 trials)
• Jacksonville Center for Clinical Research (20 trials)

The Mayo Clinic system, with its multiple designations, clearly dominates the research landscape in Jacksonville, offering a broad spectrum of studies. Facilities like Nemours Children's Clinic-Jacksonville specialize in pediatric research, while Baptist MD Anderson Cancer Center is a significant hub for oncology trials.

Impending Deadlines for Specific Conditions

Patients managing certain health conditions also face impending deadlines to join research. Trials focused on various neurological, mental health, and dermatological conditions are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Major depressive disorder (2 trials)
• Amyotrophic lateral sclerosis (2 trials)
• Aged (1 trial)
• Alzheimer disease (1 trial)
• Autonomic state (1 trial)
• Anxiety (1 trial)
• Atrial fibrillation (1 trial)
• Atopic dermatitis (1 trial)
• Attention-deficit/hyperactivity disorder (1 trial)
• Autonomic dysregulation (1 trial)

Broadening Your Search: Nearby Options

While Jacksonville offers a substantial array of clinical trial opportunities, individuals may also find options in nearby communities within Florida. Cities with active trials include Miami (16 trials), Tampa (10 trials), Orlando (6 trials), Gainesville (3 trials), Miami Lakes (3 trials), Sarasota (2 trials), Naples (2 trials), and Kissimmee (2 trials).

As we move into the spring, the focus will remain on the ongoing enrollment in these significant Phase 3 trials and the continued exploration of new therapeutic strategies, with Jacksonville's robust research community at the forefront of medical innovation.