Ann Arbor, MI Clinical Trials Report — April 2026

For Ann Arbor residents considering participation in clinical research, April 2026 presents important opportunities, particularly for those looking to join studies before enrollment concludes. Across Ann Arbor, 60 clinical trials are slated to close within the next 90 days. This urgency is especially relevant for healthy volunteers, as 9 of these rapidly closing studies are still actively seeking participants without specific health conditions. Individuals interested in contributing to medical advancements should explore these options promptly.

Ann Arbor remains a significant hub for medical research, with a total of 961 clinical trials currently recruiting across 225 research facilities this month.

Conditions with Impending Deadlines

Patients managing certain health conditions also face impending deadlines to join research. Trials focused on various cancers, inflammatory conditions, and neurological health are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Unresectable undifferentiated pleomorphic sarcoma (2 trials)
• Fibromyalgia (2 trials)
• Inflammatory bowel diseases (2 trials)
• Unresectable dedifferentiated liposarcoma (2 trials)
• Metastatic undifferentiated pleomorphic sarcoma (2 trials)
• Metastatic dedifferentiated liposarcoma (2 trials)
• Breast cancer (2 trials)
• Amyotrophic lateral sclerosis (1 trial)
• Amputation neuroma (1 trial)
• Adenoid cystic carcinoma (1 trial)

New Research Opportunities in April

This month, Ann Arbor saw the opening of 12 new clinical trials, a slight decrease from the 14 trials that launched in March 2026. This trend follows a fluctuating pattern over the past six months, with new trial openings ranging from 9 to 15 per month.

The new trials span a variety of conditions and research areas. Conditions targeted by these new studies include:

• Adolescent congenital heart disease
• Anticoagulant therapy
• BRCA1-related hereditary breast and ovarian cancer syndrome
• BRCA2-related hereditary breast and ovarian cancer syndrome
• Differentiated thyroid gland carcinoma
• Dravet syndrome
• Hereditary neoplastic syndrome
• Lynch syndrome
• Malignant testicular neoplasm

Among the new trials, several types of research are represented, including behavioral studies, drug trials, device trials, and procedure-based investigations. The majority of new trials this month are sponsored by academic institutions, with the University of Michigan and the University of Michigan Rogel Cancer Center leading with 4 new trials each. Industry sponsors like Incyte Corporation and Ionis Pharmaceuticals, Inc., along with federal sponsors like the VA Office of Research and Development, are also contributing to new research efforts.

Spotlight on Notable New Trials

April brings several high-profile new trials to Ann Arbor, including significant Phase 3 studies and large-scale observational research. These trials offer participants the chance to engage with cutting-edge treatments and diagnostic approaches across a range of health challenges.

• University of Michigan Rogel Cancer Center is sponsoring NCT07526545, "Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial." This study aims to enroll 800 participants to test how well a urine prostate cancer screening test, My Prostate Score 2 (MPS2), combined with magnetic resonance imaging (MRI), works for early detection of prostate cancer.
• Incyte Corporation is launching NCT07522073, "A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma." This important Phase 3 oncology trial seeks 588 participants to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734.
• Carelon Research is initiating NCT07525843, "A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study." This trial aims for 390 participants to learn if the WE BEAT program, a 5-week group-based online wellbeing and skill-building program, can help teens with congenital heart disease improve their ability to handle stress.
• The VA Office of Research and Development is leading NCT07507747, "Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress." This study targets 384 participants to explore how VA mobile health applications (mHealth apps) can help Veterans manage psychological distress.

Ann Arbor's Research Powerhouses

Ann Arbor is home to leading research institutions that consistently run a high volume of clinical trials. These facilities are key destinations for individuals seeking to participate in medical research:

• University of Michigan (395 trials)
• University of Michigan Rogel Cancer Center (71 trials)
• Trinity Health Saint Joseph Mercy Hospital Ann Arbor (65 trials)
• University of Michigan Comprehensive Cancer Center (39 trials)
• C S Mott Children's Hospital (33 trials)
• Research Site (27 trials)
• University of Michigan Health System (25 trials)
• University of Michigan Hospital (20 trials)
• VA Ann Arbor Healthcare System, Ann Arbor, MI (18 trials)

The University of Michigan and its associated centers, including the Rogel Cancer Center and C S Mott Children's Hospital, collectively lead the city in the number of active trials, offering a broad spectrum of research opportunities across various medical specialties.

Opportunities for Healthy Volunteers

For individuals without a specific medical condition, there are significant opportunities to contribute to medical science. Of the 12 new trials launched this month, 3 are actively seeking healthy volunteers. Across Ann Arbor, a total of 92 clinical trials are currently recruiting healthy participants, providing numerous avenues for those interested in supporting medical research.

Participation in clinical trials is open to a diverse range of individuals. Of the new trials launched this month, 3 include children, 1 is male-only, and 8 include older adults, ensuring that various demographic groups have opportunities to contribute to medical science.

Expanding Your Search: Beyond Ann Arbor

While Ann Arbor offers a vast array of clinical trial opportunities, individuals may also find options in nearby communities within Michigan. Cities with active trials include Detroit (6 trials), Troy (4 trials), Grand Rapids (1 trial), Wyoming (1 trial), and Ypsilanti (1 trial).

As we move further into spring, Ann Arbor's robust research community will continue to drive medical innovation, with ongoing enrollment in significant trials and the exploration of new therapeutic strategies. Residents are encouraged to explore these opportunities to contribute to advancements in healthcare.