Paid Clinical Trials in Worcester, MA

As of June 2026, 230 paid clinical trials are recruiting in Worcester, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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230 clinical trials

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A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

for Duchene Muscular Dystrophy

Drug: Givinostat

7 locations incl. Little Rock

Sponsor: ITF Therapeutics LLC

Sex: All·Age: 6+

Code: NCT07127978·Recruiting

Apply to this trial

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

for Ovarian Neoplasms

83 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

Apply to this trial

Social Needs Screening and Chronic Diseases Study (WE CARE)

for Hyperlipidemias

3 locations incl. Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06903897·Recruiting

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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

Drug: Duvakitug

91 locations incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184996·Phase 3·Recruiting

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Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT07072039·Recruiting

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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Duvakitug

93 locations incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184931·Phase 3·Recruiting

Apply to this trial

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for Acute Myeloid Leukemia (AML)

42 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07007312·Phase 3·Recruiting

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Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type

for Agitation

5 locations incl. Miami

Sponsor: Teikoku Pharma USA, Inc.

Sex: All·Age: All ages

Code: NCT06052254·Phase 2·Recruiting

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An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

for Guillain-Barre Syndrome

12 locations incl. Phoenix

Sponsor: Annexon, Inc.

Sex: All·Age: 12 - 85

Code: NCT07020819·Phase 3·Recruiting

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A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

17 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting

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Individualizing Treatment for Asthma in Primary Care (Full Study)

for Asthma

13 locations incl. Aurora

Sponsor: DARTNet Institute

Sex: All·Age: 13 - 75

Code: NCT07052942·Phase 4·Recruiting

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ELEVATE High-Risk PCI Pivotal Study

for High-Risk Percutaneous Coronary Intervention (High-risk PCI)

29 locations incl. Scottsdale

Sponsor: Magenta Medical Ltd.

Sex: All·Age: 18 - 88

Code: NCT07001332·Recruiting

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Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application

for Epilepsy

2 locations incl. Worcester

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18+

Code: NCT06425029·Recruiting

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Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

for Acute Myeloid Leukemia

9 locations incl. Baltimore

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06824168·Phase 2·Recruiting

Apply to this trial

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

for Alzheimer Disease

Drug: KarXT

39 locations incl. Chandler

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011745·Phase 3·Recruiting

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

65 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting

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Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

for Vascular Closure

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT06837870·Enrolling By Invitation

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for Major Depressive Disorder

35 locations incl. Dothan

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07076407·Phase 3·Recruiting

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Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

for Alcohol-Related Disorders

4 locations incl. Boston

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT05910580·Recruiting

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Radiation Free Study

for Aortic Aneurysm

5 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06549348·Recruiting

Apply to this trial

Early Detection of Gestational Diabetes Mellitus in Pregnancy

for Gestational Diabetes Mellitus in Pregnancy

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT05388643·Recruiting

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Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

for Amyotrophic Lateral Sclerosis (ALS)

15 locations incl. Phoenix

Sponsor: Brainstorm-Cell Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06973629·Phase 3·Not Yet Recruiting

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

for Dystrophic Epidermolysis Bullosa

5 locations incl. Rancho Santa Margarita

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 6 Months+

Code: NCT07016750·Phase 3·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

67 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06958211·Phase 3·Recruiting

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A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

for Facioscapulohumeral Muscular Dystrophy

14 locations incl. Orange

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16 - 70

Code: NCT07038200·Phase 3·Recruiting

Apply to this trial

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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Preventing T2DM After GDM With Immediate Postpartum Screening

for Gestational Diabetes

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06457139·Recruiting

Apply to this trial

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

139 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

for Advanced High-Grade Epithelial Ovarian Cancer

7 locations incl. Sarasota

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06682988·Phase 2·Recruiting

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

386 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for Lower Extremity Acute Limb Ischemia

31 locations incl. Scottsdale

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT06747117·Recruiting

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Moms@Home: A Storytelling-based Mobile Health Intervention to Improve Blood Pressure Management in Pregnancy

for Hypertension in Pregnancy

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18 - 50

Code: NCT06835959·Recruiting

Apply to this trial

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

for Facioscapulohumeral Muscular Dystrophy

5 locations incl. Los Angeles

Sponsor: Epicrispr Biotechnologies, Inc.

Sex: All·Age: 18 - 75

Code: NCT06907875·Phase 1, Phase 2·Recruiting

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A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy (IgAN)

28 locations incl. Little Rock

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT06935357·Phase 3·Recruiting

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Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

48 locations incl. Birmingham

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting

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PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for Progressive Pulmonary Fibrosis

5 locations incl. Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18 - 80

Code: NCT06855329·Recruiting

Apply to this trial

Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma

for Age-Related Macular Degeneration

1 location in Worcester

Sponsor: MCPHS University

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06593405·EARLY_Phase 1·Recruiting

Apply to this trial