Paid Clinical Trials in Tennessee

Tennessee has 2,157 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,157 clinical trials

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SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

for Hemophilia A With Inhibitor

21 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: 12 - 100

Code: NCT04647227·Phase 4·Recruiting

Apply to this trial

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

57 locations incl. Long Beach

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

12 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: Female·Age: 18+

Code: NCT04802759·Phase 1, Phase 2·Recruiting

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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for Pancreatic Acinar Cell Carcinoma

451 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04858334·Phase 2·Recruiting

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SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

for Low-Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 2 - 24

Code: NCT04923126·Phase 1, Phase 2·Recruiting

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Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

for Coronary Artery Disease

40 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT04451044·Enrolling By Invitation

ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

53 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting

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A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for Prostate Cancer

24 locations incl. Tucson

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT04729114·Phase 1·Recruiting

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Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

for Recurrent Solid Tumor

7 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12 Months - 30

Code: NCT04901702·Phase 1, Phase 2·Recruiting

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

18 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting

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A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

for Advanced Solid Tumor

6 locations incl. Lake Mary

Sponsor: Edgewood Oncology Inc.

Sex: All·Age: 18+

Code: NCT04872166·Phase 1·Recruiting

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Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

for Alopecia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 7+

Code: NCT04764357·Recruiting

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Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

for Parkinson Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40+

Code: NCT04715984·Recruiting

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Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

for Breast Cancer

7 locations incl. Washington D.C.

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04841148·Phase 2·Recruiting

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A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for Cervical Cancer

11 locations incl. Clovis

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT04895709·Phase 1, Phase 2·Recruiting

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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

for Tibial Fractures

13 locations incl. Indianapolis

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 80

Code: NCT07006675·Phase 3·Recruiting

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A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

26 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting

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Goal-Directed Sedation in Mechanically Ventilated Infants and Children

for Delirium

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 44 Weeks - 11

Code: NCT04801589·Phase 3·Recruiting

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Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

for Locally Advanced (Inoperable) or Metastatic Breast Cancer

54 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT04862663·Phase 3·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

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Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

for Peripheral Arterial Disease

19 locations incl. New Haven

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT04774159·Phase 3·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

for Chronic Lymphocytic Leukemia (CLL)

16 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04830137·Phase 1·Recruiting

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A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

for Ventilator Associated Pneumonia

8 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT04987840·Enrolling By Invitation

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

6 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

12 locations incl. Phoenix

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting

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Neural Correlates of Psychiatric Disorders

for Psychiatric Disorder

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04725409·Recruiting

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Abatacept for the Treatment of Giant Cell Arteritis

for Giant Cell Arteritis

5 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 50+

Code: NCT04474847·Phase 3·Recruiting

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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

for Kidney Disease, End-Stage

16 locations incl. La Jolla

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT04634916·Recruiting

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Intraoperative Optical Coherence Tomography - Normals

for Healthy Volunteers

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04790890·Enrolling By Invitation

Fenofibrate for Prevention of DR Worsening

for Diabetic Retinopathy

66 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18 - 80

Code: NCT04661358·Phase 3·Recruiting

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

31 locations incl. Phoenix

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting

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Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

10 locations incl. Iowa City

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting

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A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

for Advanced Malignant Solid Neoplasm

3 locations incl. Los Angeles

Sponsor: RasCal Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04678648·Phase 1·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

620 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

Apply to this trial