Paid Clinical Trials in Tennessee

Tennessee has 2,155 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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2,155 clinical trials

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A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for Geographic Atrophy

15 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT05626114·Phase 2·Recruiting

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A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for Solid Tumor, Adult

13 locations incl. Los Angeles

Sponsor: GV20 Therapeutics

Sex: All·Age: 18+

Code: NCT05669430·Phase 1, Phase 2·Recruiting

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Childhood Cancer Survivors' Affective Response to Exercise

for ALL, Childhood

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 39

Code: NCT05763290·Recruiting

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Dysregulation of Whole-body Metabolism in Ovarian Cancer: A Longitudinal Study

for Ovary Cancer

1 location in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female·Age: 18+

Code: NCT06800105·Recruiting

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A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

26 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05650632·Phase 1·Recruiting

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Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

for Von Willebrand Diseases

10 locations incl. Los Angeles

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 60·Accepts healthy volunteers

Code: NCT05776069·Phase 1, Phase 2·Recruiting

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A Study of ASP1002 in Adults for Treatment of Solid Tumors

for Advanced Solid Tumors

15 locations incl. New Haven

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05719558·Phase 1·Recruiting

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

176 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies

for Advanced or Metastatic Solid Tumors

11 locations incl. Scottsdale

Sponsor: Incendia Therapeutics

Sex: All·Age: 18+

Code: NCT05753722·Phase 1·Recruiting

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Longitudinal Study for Central Nervous System Vasculitis

for Central Nervous System Vasculitis

4 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05734404·Recruiting

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Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation

for Head and Neck Cancer

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05650710·Recruiting

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A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

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Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

for Postural Tachycardia Syndrome (POTS)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05375968·Phase 2·Recruiting

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

9 locations incl. Phoenix

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

3 locations incl. Duarte

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting

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REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19

for COVID-19

5 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05218083·Recruiting

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A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

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Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

for Ductus Arteriosus, Patent

24 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 7 Days - 32 Days

Code: NCT05547165·Recruiting

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

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A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

for HR+/HER2-negative Breast Cancer

9 locations incl. Chicago

Sponsor: Totus Medicines

Sex: Female·Age: 18+

Code: NCT05683418·Phase 1·Recruiting

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(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

for Breast Neoplasms

15 locations incl. Phoenix

Sponsor: Atossa Therapeutics, Inc.

Sex: Female·Age: 18+

Code: NCT05607004·Phase 2·Recruiting

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Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

for Relapsed Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05713214·Recruiting

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Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study

for Clonal Cytopenia of Undetermined Significance

Drug: Canakinumab

6 locations incl. Miami

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT05641831·Phase 2·Recruiting

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CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

16 locations incl. Birmingham

Sponsor: Caribou Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05722418·Phase 1·Recruiting

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Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

for Advanced Lung Neuroendocrine Tumor

29 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04665739·Phase 2·Recruiting

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A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

for HER2-positive Breast Cancer

14 locations incl. Los Angeles

Sponsor: Mersana Therapeutics

Sex: All·Age: 18+

Code: NCT05514717·Phase 1·Recruiting

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Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

for Neurodegenerative Diseases

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 50 - 85·Accepts healthy volunteers

Code: NCT05357612·Phase 4·Recruiting

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Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

for Pulmonary Arterial Hypertension

10 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 - 17

Code: NCT05587712·Phase 2·Recruiting

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Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

for Idiopathic Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05462574·Recruiting

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

Apply to this trial

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

for Hormone Receptor-positive Breast Cancer

7 locations incl. New Haven

Sponsor: Ellipses Pharma

Sex: Female·Age: 18+

Code: NCT05573126·Phase 1, Phase 2·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. San Francisco

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

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A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

18 locations incl. Loma Linda

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05592626·Phase 1, Phase 2·Recruiting

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The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study

for Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05464095·Recruiting

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Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study

for Breast Cancer

17 locations incl. Greenbrae

Sponsor: Tolmar Inc.

Sex: All·Age: 18 - 51

Code: NCT05645536·Phase 3·Enrolling By Invitation