Dysregulation of Whole-body Metabolism in Ovarian Cancer: A Longitudinal Study

Part of paid clinical trials in Knoxville, Tennessee.

Sponsor
University of Tennessee Graduate School of Medicine
Study ID
NCT06800105
Status
Recruiting
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Conditions

  • Ovary Cancer

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • High fat smoothie — OTHER
    Participants will consume a standardized 490 kcal high-fat smoothie, consisting of 57% fat, 23% carbohydrate, and 20% protein.

Study Details

Minimal information is available regarding changes in whole-body metabolism in ovarian cancer patients, and no study has assessed whole-body lipid metabolism in this patient population. In this pilot study we will assess fasting and postprandial lipid metabolism of ovarian cancer patients before, during, and after treatment via indirect calorimetry.

Key Dates

Start date
Mar 22, 2023
Status verified
Jan 2025
Primary completion
Mar 31, 2027
Completion
Mar 31, 2028

Study Design

Enrollment
10 participants (estimated)

Arms

  • Arm: Patients with presumed ovarian cancer
    Patients with presumed ovarian cancer will complete three, 4-hour study visits at the following time points: * The 1st visit will occur before treatment. * The 2nd visit will occur after about half of the planned treatment as been completed. * The 3rd visit will occur 4-8 weeks after the completion of treatment.

Primary Outcome Measure

Feasibility assessed by attrition [ Time Frame: 60 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Tennessee Graduate School of MedicineKnoxvilleTennessee37920
Jill M Maples, PhD
[email protected]

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University of Tennessee Graduate School of Medicine· Knoxville, TN

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