Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,155 clinical trials

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A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for T-cell Acute Lymphoblastic Leukemia

13 locations incl. Duarte

Sponsor: Wugen, Inc.

Sex: All·Age: 1+

Code: NCT06514794·Phase 2·Recruiting

Apply to this trial

Nemaline Myopathy Clinical Research Network (NM-CTRN)

for Nemaline Myopathy

5 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: 0 - 18

Code: NCT06774703·Not Yet Recruiting

Evaluation of Eye Gaze Sharing in the Operating Room

for Kidney Stones

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07173309·Recruiting

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

464 locations incl. Fairbanks

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

53 locations incl. Birmingham

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting

Apply to this trial

Validity of Viome's Oral/throat Cancer Test

for Oral and Throat Cancer

2 locations incl. St Louis

Sponsor: Viome

Sex: All·Age: 18+

Code: NCT06174428·Recruiting

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A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

for Diffuse Large B-Cell Lymphoma

Drug: Rituximab

42 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06717347·Phase 3·Recruiting

Apply to this trial

Making Healthy Habits Stick

for Cancer

2 locations incl. Birmingham

Sponsor: University of Tennessee

Sex: Female·Age: 19+

Code: NCT06745180·Recruiting

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A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

80 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting

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Evaluating the Effectiveness of a Multi-level Health-Related Social Needs Initiative

for Type 2 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06831162·Enrolling By Invitation

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

66 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

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Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

for Acute Lymphoblastic Leukemia

2 locations incl. Tulsa

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 18

Code: NCT06533748·Phase 2·Recruiting

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A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

for Geographic Atrophy

65 locations incl. Phoenix

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: All ages

Code: NCT06779773·Recruiting

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A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for Chronic Graft-versus-host-disease

33 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06585774·Phase 3·Recruiting

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A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

for SLE

10 locations incl. Avondale

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT06613360·Phase 1·Recruiting

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A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non-Small Cell Lung Cancer

Drug: Telisotuzumab Vedotin

38 locations incl. Chandler

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06568939·Phase 2·Recruiting

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Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for Vestibular Schwannoma

4 locations incl. Baltimore

Sponsor: Akouos, Inc.

Sex: All·Age: 18+

Code: NCT06517888·Phase 1, Phase 2·Recruiting

Apply to this trial

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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Complications Related To Activity After Pediatric Both Bone Fractures: Exploring the Effects of Activity on Fracture Displacement

for Forearm Fractures (Both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 8 - 18

Code: NCT06799377·Recruiting

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Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy

for Schizophrenia Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT06835556·Recruiting

Apply to this trial

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for Breast Cancer

17 locations incl. Prescott

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06695845·Phase 2·Recruiting

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. Los Angeles

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06589596·Phase 1·Recruiting

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A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

for Sickle Cell Disease

Drug: Etavopivat

39 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 2+

Code: NCT06609226·Phase 3·Recruiting

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

23 locations incl. Phoenix

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting

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Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

for CTCL/ Mycosis Fungoides

17 locations incl. Phoenix

Sponsor: Soligenix

Sex: All·Age: 18+

Code: NCT06470451·Phase 3·Recruiting

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Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

for Non-small Cell Lung Cancer

36 locations incl. Anchorage

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712316·Phase 2, Phase 3·Recruiting

Apply to this trial

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

for Neoplasm

7 locations incl. New Haven

Sponsor: Compugen Ltd

Sex: All·Age: 18+

Code: NCT06759649·Phase 1·Recruiting

Apply to this trial

Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

for Delirium

14 locations incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06192615·Phase 3·Recruiting

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The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life

for Systemic Sclerosis (SSc)

4 locations incl. New Orleans

Sponsor: Robyn T. Domsic, MD, MPH

Sex: All·Age: 18+

Code: NCT06675344·Recruiting

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A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

21 locations incl. Chandler

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06588478·Phase 2·Recruiting

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InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

for Respiratory Distress Syndrome (Neonatal)

10 locations incl. Phoenix

Sponsor: ONY

Sex: All·Age: 29 Weeks - 36 Weeks

Code: NCT05960929·Phase 3·Recruiting

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Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

for Fracture of Tibia

6 locations incl. Baltimore

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18+

Code: NCT06337292·Phase 3·Recruiting

Apply to this trial

A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage

for Post Partum Hemorrhage

1 location in Nashville

Sponsor: Holly Ende

Sex: Female·Age: All ages

Code: NCT06513351·Recruiting

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Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)

for Pulmonary Embolism Acute

12 locations incl. Thousand Oaks

Sponsor: Akura Medical

Sex: All·Age: 18+

Code: NCT06672510·Recruiting

Apply to this trial

Postoperative Bladder Filling After Outpatient Laparoscopic Hysterectomy and Time to Discharge

for Patient Discharge

1 location in Memphis

Sponsor: University of Tennessee

Sex: Female·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06737393·Recruiting

Apply to this trial

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

for Preeclampsia

1 location in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female·Age: 18 - 45

Code: NCT06802861·Recruiting

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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

43 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting

Apply to this trial