Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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Tube Size Randomized Trial During Emergency Tracheal Intubation

for Acute Respiratory Failure

7 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06939361·Enrolling By Invitation

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

6 locations incl. Scottsdale

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting

Apply to this trial

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

for Inflammatory Bowel Disease (IBD)

6 locations incl. New Orleans

Sponsor: Mercy Medical Center

Sex: All·Age: 18+

Code: NCT06750731·Recruiting

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WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

26 locations incl. Birmingham

Sponsor: Mediar Therapeutics

Sex: All·Age: 40+

Code: NCT06967805·Phase 2·Recruiting

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Arterial Stiffness and Blood Pressure

for Hypertension

3 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT06495710·Recruiting

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Tirzepatide in PWS, HO and GNSO

for Prader-Willi Syndrome

Drug: Tirzepatide

3 locations incl. Saint Paul

Sponsor: Grace Kim

Sex: All·Age: 18 - 26

Code: NCT06901245·Phase 4·Recruiting

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A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

for Solid Tumor

11 locations incl. San Francisco

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06952010·Phase 1·Recruiting

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Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

for Atherosclerotic Cardiovascular Disease (ASCVD)

Drug: Inclisiran

37 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT06813911·Phase 3·Recruiting

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Atomoxetine in Melanocortin Obesity Syndrome

for Melanocortin Obesity Syndrome

2 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 6+

Code: NCT06899178·Phase 2·Not Yet Recruiting

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

for Triple Negative Breast Cancer

9 locations incl. Los Angeles

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06926920·Phase 1, Phase 2·Recruiting

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Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

for Hematuria - Cause Not Known

15 locations incl. Homewood

Sponsor: Pacific Edge Limited

Sex: All·Age: 18 - 88

Code: NCT06394869·Recruiting

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

49 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting

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CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06777979·Phase 1·Recruiting

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Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy

for Cancer Weight Loss

25 locations incl. Tucson

Sponsor: Endevica Bio

Sex: All·Age: 18+

Code: NCT06937177·Phase 2·Recruiting

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Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

for Locally Advanced/Metastatic Solid Tumors

5 locations incl. Denver

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06414460·Phase 1·Recruiting

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Project VOICES: Vocal Optimization in Children Elevating the Spectrum

for Autism

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 2 - 5

Code: NCT06875843·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

9 locations incl. Los Angeles

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting

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Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

40 locations incl. Ames

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06232044·Phase 1, Phase 2·Recruiting

Apply to this trial

MMA Embolization for Refractory Chronic Migraine

for Migraine Disorders

9 locations incl. Phoenix

Sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.

Sex: All·Age: 18 - 65

Code: NCT06735833·Recruiting

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A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

for Alagille Syndrome

10 locations incl. Los Angeles

Sponsor: Ipsen

Sex: All·Age: All ages

Code: NCT06850038·Recruiting

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Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

10 locations incl. Huntsville

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting

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An Interventional Study of Infigratinib in Children With Hypochondroplasia

for Hypochondroplasia

7 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT06873035·Phase 2, Phase 3·Enrolling By Invitation

Swallowing Impairments in Adults With and Without Alzheimer's Disease

for Alzheimer Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06678100·Recruiting

Apply to this trial

Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

for Insomnia Disorder

21 locations incl. Dothan

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06953869·Phase 3·Recruiting

Apply to this trial

Pivotal Study of Voro Urologic Scaffold

for Radical Prostatectomy

19 locations incl. Phoenix

Sponsor: Levee Medical, Inc.

Sex: Male·Age: 45+

Code: NCT06873581·Phase 3·Recruiting

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Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

for HNSCC

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06819228·EARLY_Phase 1·Recruiting

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A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)

for New Onset Generalized Myasthenia Gravis (gMG)

Drug: Efgartigimod PH20 SC

18 locations incl. La Jolla

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06909214·Phase 4·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

Apply to this trial

Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses

for Contact Lens Comfort

1 location in Memphis

Sponsor: Southern College of Optometry

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06955403·Recruiting

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A Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma Treatment

for Melanoma

7 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06848088·Phase 2·Enrolling By Invitation

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for Hepatocellular Cancer

10 locations incl. Duarte

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06858813·Phase 1·Recruiting

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Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

for Psoriatic Arthritis

16 locations incl. Huntington Beach

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06865105·Phase 2·Recruiting

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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for Ovarian Cancer

30 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06824467·Phase 3·Recruiting

Apply to this trial

Brief Interventions to Improve Behavior Outcomes and Prevent Cavities

for Parenting

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 9 Months - 3·Accepts healthy volunteers

Code: NCT06588725·Enrolling By Invitation

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

for ALS

10 locations incl. La Jolla

Sponsor: Amylyx Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06665165·Phase 1·Recruiting

Apply to this trial

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

for AML

4 locations incl. Sacramento

Sponsor: CERo Therapeutics Holdings, Inc.

Sex: All·Age: 18 - 85

Code: NCT06834282·Phase 1·Recruiting

Apply to this trial