Oncology Clinical Trials in Tampa, FL

As of June 2026, 286 paid clinical trials are recruiting for Oncology in Tampa, Florida. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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286 clinical trials for Oncology

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Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

for Melanoma Stage III

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06295159·Phase 2·Recruiting

Apply to this trial

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

for Pediatric Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: All ages

Code: NCT06423950·Recruiting

Apply to this trial

Study of REM-422 in Patients With AML or Higher Risk MDS

for Myelodysplastic Syndromes

5 locations incl. Duarte

Sponsor: Remix Therapeutics

Sex: All·Age: 18+

Code: NCT06297941·Phase 1·Recruiting

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Duarte

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting

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Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

for Follicular Lymphoma

Drug: Rituximab

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06350318·Phase 2·Recruiting

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A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

17 locations incl. San Francisco

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting

Apply to this trial

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

for Ovarian Cancer

17 locations incl. Duarte

Sponsor: Xencor, Inc.

Sex: All·Age: 15+

Code: NCT06276491·Phase 1·Recruiting

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A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

16 locations incl. Fountain Valley

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05932862·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

for Solid Tumor, Adult

12 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06051695·Phase 1, Phase 2·Recruiting

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Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

44 locations incl. Homewood

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting

Apply to this trial

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

Apply to this trial

A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

for Advanced Solid Tumor

20 locations incl. Irvine

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06244485·Phase 1·Recruiting

Apply to this trial

Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer

for Pancreatic Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06423963·Recruiting

Apply to this trial

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

30 locations incl. Daphne

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06095505·Phase 2·Recruiting

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QTX3034 in Patients With KRAS G12D Mutation

for Solid Tumors

14 locations incl. Los Angeles

Sponsor: Quanta Therapeutics

Sex: All·Age: 18+

Code: NCT06227377·Phase 1·Recruiting

Apply to this trial

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

for Glioblastoma

19 locations incl. Phoenix

Sponsor: CarThera

Sex: All·Age: 18+

Code: NCT05902169·Phase 3·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

for GastroEsophageal Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06109467·Phase 2·Recruiting

Apply to this trial

Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer

for Breast Cancer

5 locations incl. Miami Beach

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT05950945·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

for Non-small Cell Lung Cancer

9 locations incl. Glendale

Sponsor: Teligene US

Sex: All·Age: 18+

Code: NCT06010329·Phase 2·Recruiting

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Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for B-Cell Lymphoblastic Leukemia

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06144606·Phase 2·Recruiting

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

11 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

Apply to this trial

Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

for Squamous Cell Carcinoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06137274·Phase 2·Recruiting

Apply to this trial

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for Non-small Cell Lung Cancer

Drug: Intismeran autogene

68 locations incl. Anchorage

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06077760·Phase 3·Recruiting

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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

16 locations incl. Davis

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting

Apply to this trial

Blue-Button Regional Trial Screening

for Cancer

2 locations incl. Tampa

Sponsor: American Cancer Society Cancer Action Network

Sex: All·Age: 18+

Code: NCT05885880·Enrolling By Invitation

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

for Soft Tissue Sarcoma

26 locations incl. Phoenix

Sponsor: Polaris Group

Sex: All·Age: 18 - 99

Code: NCT05712694·Phase 3·Recruiting

Apply to this trial

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

22 locations incl. Santa Monica

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting

Apply to this trial

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for Non-Small Cell Lung Cancer (NSCLC)

Drug: daraxonrasib

21 locations incl. Duarte

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06128551·Phase 1, Phase 2·Recruiting

Apply to this trial

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

for Large B-cell Lymphoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06104592·Phase 2·Recruiting

Apply to this trial

Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)

for Rectal Cancer

1 location in Tampa

Sponsor: University of South Florida

Sex: All·Age: 18 - 100

Code: NCT06380101·Recruiting

Apply to this trial

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

17 locations incl. Sacramento

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06040541·Phase 1·Recruiting

Apply to this trial

Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. New Haven

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting

Apply to this trial

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

10 locations incl. Los Angeles

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting

Apply to this trial

Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)

for Pancreatic Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06001268·Recruiting

Apply to this trial

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for B-cell Malignancy

13 locations incl. Orange

Sponsor: Carna Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05602363·Phase 1·Recruiting

Apply to this trial

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

8 locations incl. Jacksonville

Sponsor: Vividion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05954312·Phase 1·Recruiting

Apply to this trial

Conditions in Oncology (Tampa, FL)

Solid tumor· 39 Non-small cell lung cancer (NSCLC)· 38 Breast cancer· 31 Cancer (any)· 20 Colorectal cancer· 19 Pancreatic cancer· 19 Acute myeloid leukemia (AML)· 16 Myelodysplastic syndromes (MDS)· 15 Ovarian cancer· 14 Multiple myeloma· 14 Melanoma· 14 Prostate cancer· 13 Metastatic breast cancer· 11 Non-Hodgkin lymphoma· 11 Triple-negative breast cancer· 10 Endometrial cancer· 10 Leukemia (other)· 10 Head and neck cancer· 10 Metastatic prostate cancer· 8 Acute lymphoblastic leukemia· 8 Hematologic malignancy· 8 Diffuse large B-cell lymphoma (DLBCL)· 7 Liver cancer· 6 Biliary tract cancer· 6 Glioblastoma· 6 Follicular lymphoma· 6 HER2-positive breast cancer· 5 HER2-negative breast cancer· 5 Lung cancer· 5 Bladder cancer· 5 Fallopian tube cancer· 5 Glioma· 5 Chronic lymphocytic leukemia (CLL)· 5 Mantle cell lymphoma· 5 Neuroblastoma· 5 Colon cancer· 4 Gastric cancer· 4 Esophageal cancer· 4 Gastroesophageal junction cancer· 4 Brain cancer· 4 Myelofibrosis· 4 Marginal zone lymphoma· 4 Osteosarcoma· 4 Small cell lung cancer· 3 Metastatic colorectal cancer· 3 Rectal cancer· 3 Kidney cancer· 3 Myeloproliferative neoplasm· 3 Small lymphocytic lymphoma· 3 Skin cancer· 3 Thyroid cancer· 3 Sarcoma· 3 Gastrointestinal cancer· 2 Brain metastases· 2 Soft tissue sarcoma· 2 Ewing sarcoma· 2 Pediatric cancer· 2 Mesothelioma· 2 Neuroendocrine tumors· 2 Cervical cancer· 1 Chronic myelomonocytic leukemia· 1 Hodgkin lymphoma· 1 Rhabdomyosarcoma· 1