Breast oncology Clinical Trials in Tampa, FL
As of June 2026, 50 paid clinical trials are recruiting for Breast oncology in Tampa, Florida. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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50 clinical trials for Breast oncology
·Clear filters·↓ Download CSVPhase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
The MIND-BC Study: MIND Diet for Breast Cancer Cognition
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer
A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
PRE-I-SPY Phase I/Ib Oncology Platform Program
Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
A Study of XMT-1660 in Participants With Solid Tumors
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer
MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
About research studies in Tampa
Tampa has approximately 1,113 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Tampa
Researchers run research studies in Tampa, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Moffitt Cancer Center | Breast Cancer, Pancreatic Cancer, Triple Negative Breast Cancer | 293 |
| University of South Florida | Heart Failure, Myasthenia Gravis, Multiple Sclerosis | 127 |
| Tampa General Hospital | Heart Failure, Kidney Transplant Rejection, Acute Myeloid Leukemia | 74 |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia | 40 |
| Moffitt Cancer Center - McKinley Campus | Stage IV Lung Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain, Stage IIIB Lung Cancer AJCC v8 | 28 |
| Moffitt Cancer Center-International Plaza | Stage IV Lung Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain, Stage IIIB Lung Cancer AJCC v8 | 24 |
| Moffit Cancer Center | Unresectable Metastatic Colorectal Cancer, Esophageal Cancer, Gastric Cancer (GC) | 14 |
| St. Joseph's Children's Hospital | Neuroblastoma, Medulloblastoma, Ewing Sarcoma | 9 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia, Tardive Dyskinesia | 8 |
| K2 Medical Research - Tampa | Alcohol Use Disorder, Alzheimer Disease, Dementia | 8 |
| USF Health | Epilepsy, Epilepsy (Treatment Refractory), Asthma | 8 |
| H. Lee Moffitt Cancer Center and Research Institute | Breast Neoplasms, Gastroesophageal Junction Adenocarcinoma, Metastatic Breast Cancer | 7 |
| AdventHealth Tampa | Heart Failure, ADHF, Anastomotic Leak | 6 |
| GSK Investigational Site | Chickenpox, Gastrointestinal Neoplasms, HIV Infections | 6 |
| International Center for Research | C. Diff Infection, C.Difficile Diarrhea, CDI | 6 |
| Retina Associates of Florida, LLC | Age-Related Macular Degeneration, Choroidal Neovascularization, Diabetic Macular Edema | 6 |
| Florida Urology Partners | Prostate Cancer, Benign Prostatic Hyperplasia, Bladder Pain Syndrome | 5 |
| ForCare Clinical Research | Atopic Dermatitis, Acute Treatment of Migraine, Eczema | 5 |
| GCP Clinical Research | Crohn Disease, Colitis, Ulcerative | 5 |
| Genesis Clinical Research | Atherosclerotic Cardiovascular Disease in Patients With ESKD, Chronic Kidney Diseases, Healthy | 5 |
| Pediatric Epilepsy and Neurology Specialists | Developmental and Epileptic Encephalopathy, Dravet Syndrome, Lennox Gastaut Syndrome | 5 |
| Clinical Trial Site | Hypertension, Advanced Solid Cancer, Generalized Myasthenia Gravis | 4 |
| Florida Orthopaedic Institute | Osteoarthritis, Carpal Tunnel Syndrome (CTS), Carpometacarpal (CMC) Joint Arthritis | 4 |
| Foundation for Orthopaedic Research and Education | Adhesive Capsulitis of Shoulder, Back Pain, Degenerative Disc Disease | 4 |
| H Lee Moffitt Cancer Center | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Advanced or Metastatic Colorectal Cancer | 4 |
Active & Upcoming Studies in Tampa (2026)
Recruiting trials in Tampa grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (403 active studies)
- PRehabilitation Intervention to Modify Eating for Breast Cancer Patients (PRIME) · H. Lee Moffitt Cancer Center and Research Institute
- Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation · Phase 1, Phase 2 · National Cancer Institute (NCI)
Neurology & pain (68 active studies)
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up · Epiminder America, Inc.
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
Cardiovascular (50 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System · P+F Products + Features USA Inc.
Diabetes & metabolic (34 active studies)
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
- Modifying Diet to Improve Gut Microbiome · H. Lee Moffitt Cancer Center and Research Institute
Mental health & behavior (31 active studies)
- The WeACT Program for Family Caregivers of People Living With Dementia · University of South Florida
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
Eye & vision (10 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Pediatric (10 active studies)
HIV / STI (8 active studies)
- Combatting HIV Or Other STIs Early (CHOOSE) · Phase 2 · Westat
- REINItiation of Antiretroviral Therapy Using Oral bicTegravir, emtrIcitAbine and Tenofovir alafenamidE · Phase 4 · CAN Community Health
Vaccines (6 active studies)
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
- Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses · BioFire Defense LLC
Common conditions studied in Tampa
- Breast Cancer (24 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (15 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Colorectal Cancer (15 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Heart Failure (15 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Cancer (14 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Multiple Myeloma (13 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Tampa
- H. Lee Moffitt Cancer Center and Research Institute
- University of South Florida
- AstraZeneca
- Eli Lilly and Company
- National Cancer Institute (NCI)
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Tampa. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Tampa
Hipa.ai aggregates every recruiting study in Tampa from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Tampa?
There are approximately 1,113 recruiting clinical trials in Tampa, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Tampa pay participants?
Most recruiting trials in Tampa compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Tampa?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Tampa?
The most common conditions under active study in Tampa include Breast Cancer (24), Acute Myeloid Leukemia (15), Colorectal Cancer (15), Heart Failure (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Tampa?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tampa on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Tampa?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Tampa?
Recruiting research sites in Tampa include Moffitt Cancer Center, University of South Florida, Tampa General Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Tampa right now?
The largest active categories in Tampa are Cancer & tumors (403), Neurology & pain (68), Cardiovascular (50). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.