Clinical Trials at Washington University School of Medicine
As of June 2026, 484 paid clinical trials are recruiting at Washington University School of Medicine, located at Washington University School of Medicine, 1 Children's Pl, St. Louis, MO 63110, phone (314) 454-6215 in St Louis, Missouri. Active studies at this site cover conditions such as Breast Cancer, Prostate Cancer and Heart Failure. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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484 clinical trials at Washington University School of Medicine
·Clear filters·↓ Download CSVTesting the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer
ATRN-119 in Combination With Decitabine in Patients With TP53-Mutated AML or Higher-Risk MDS
Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer
Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer
DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer
ENGAGE-TBI Feasibility Study
Low-Count Quantitative SPECT for Men Treated With Radium-223
Rivastigmine for Antimuscarinic Delirium
PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma
Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer
Precision Supplemental Imaging in Women With Dense Breasts
Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients
First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer
Overcoming Racial Disparities in Screening Mammography
Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Psilocybin-Assisted Therapy as a Treatment for Depression
Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer
Lumateperone for Late-Life Depression
DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy
Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)
Feasibility of SUPPORT-TBI
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
CARE Tool Study Aim 3
Weight Gain in Pediatric Leukemia Survivors
Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma
Motixafortide for MRD Sensitization in AML
Multicontext Approach for Cognitive Function in Parkinson Disease
Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen
Therapeutic RSK1 Targeting in Myelofibrosis
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study
Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)
5-Fluorouracil Response and Optimization STudy (The FROST Trial)
Feasibility of HPV Self-Collection Kits for Cervical Cancer Screening
Transcutaneous Auricular Vagus Nerve Stimulation for Attenuation of Inflammatory Response and Blood Pressure in Type B Aortic Dissection
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
About research studies in St Louis
St Louis has approximately 1,462 recruiting research studies across a wide range of therapeutic areas. Missouri hosts Washington University School of Medicine in St. Louis and University of Kansas Medical Center's Missouri partners, known for oncology, genomics, and rare-disease research.
Common conditions studied in St Louis
- Breast Cancer (36 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (29 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Heart Failure (23 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Colorectal Cancer (22 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Advanced Solid Tumor (21 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Alzheimer Disease (20 active studies). Alzheimer's research investigates anti-amyloid antibodies, tau-targeted therapies, and lifestyle interventions aimed at slowing cognitive decline.
Leading research sponsors in St Louis
- Washington University School of Medicine
- National Cancer Institute (NCI)
- AstraZeneca
- Eli Lilly and Company
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Missouri are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Missouri research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in St Louis. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in St Louis
Hipa.ai aggregates every recruiting study in St Louis from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in St Louis?
There are approximately 1,462 recruiting clinical trials in St Louis, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in St Louis pay participants?
Most recruiting trials in St Louis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in St Louis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in St Louis?
The most common conditions under active study in St Louis include Breast Cancer (36), Prostate Cancer (29), Heart Failure (23), Colorectal Cancer (22), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in St Louis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in St Louis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in St Louis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in St Louis?
Recruiting research sites in St Louis include Washington University School of Medicine, Washington University, Mercy Hospital Saint Louis, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in St Louis right now?
The largest active categories in St Louis are Cancer & tumors (552), Neurology & pain (99), Cardiovascular (66). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Washington University School of Medicine?
Washington University School of Medicine is located at Washington University School of Medicine, 1 Children's Pl, St. Louis, MO 63110. Use the Google Maps link in the intro above to get directions.
How do I contact Washington University School of Medicine?
You can reach Washington University School of Medicine by phone at (314) 454-6215. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.