Clinical Trials at Seattle Children's Hospital

As of June 2026, 194 paid clinical trials are recruiting at Seattle Children's Hospital, located at 4800 SAND POINT WAY NE, 818-RC, SEATTLE, WA 98105-3901, phone (206) 987-2000 in Seattle, Washington. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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194 clinical trials at Seattle Children's Hospital

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Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

for Heart Failure

5 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: 0 - 16

Code: NCT06080074·Phase 2·Recruiting

Apply to this trial

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

Apply to this trial

A Trial to Improve Family Clinical Note Access and Outcomes for Hospitalized Children

for Hospitalized Child

3 locations incl. Los Angeles

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT06722378·Recruiting

Apply to this trial

Study of Olutasidenib and Temozolomide in HGG

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Rigel Pharmaceuticals

Sex: All·Age: 12 - 39

Code: NCT06161974·Phase 2·Recruiting

Apply to this trial

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

Apply to this trial

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

11 locations incl. Los Angeles

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting

Apply to this trial

Sodium Awareness in Lactation Trial

for Breastfeeding

2 locations incl. Seattle

Sponsor: The Hospital for Sick Children

Sex: Female·Age: All ages

Code: NCT06563726·Recruiting

Apply to this trial

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

for Hypogonadism, Male

20 locations incl. Los Angeles

Sponsor: Halozyme Therapeutics

Sex: Male·Age: 12 - 17

Code: NCT06689085·Phase 3·Recruiting

Apply to this trial

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

190 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting

Apply to this trial

The "What Is Important to Us" Communication Intervention Pilot Clinical Trial

for Critical Illness

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 6 Months+

Code: NCT06208332·Phase 2·Recruiting

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

19 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting

Apply to this trial

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for T-cell Acute Lymphoblastic Leukemia

13 locations incl. Duarte

Sponsor: Wugen, Inc.

Sex: All·Age: 1+

Code: NCT06514794·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

80 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting

Apply to this trial

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting

Apply to this trial

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

13 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting

Apply to this trial

REACT-01: Reversing Autoimmunity Through Cell Therapy

for Systemic Lupus Erythematosus

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 2 - 30

Code: NCT06465147·Phase 1·Recruiting

Apply to this trial

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

13 locations incl. Tucson

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting

Apply to this trial

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

Apply to this trial

Using Ecological Momentary Assessment to Develop an Adaptive Psychological Intervention for Young Adults With Chronic Pain

for Chronic Pain

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18 - 25

Code: NCT06932432·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

for Migraine

Drug: Rimegepant

27 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT06616194·Phase 3·Recruiting

Apply to this trial

The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program

for Influenza

2 locations incl. Chicago

Sponsor: University of Colorado, Denver

Sex: All·Age: 6 Months - 99·Accepts healthy volunteers

Code: NCT05832307·Recruiting

Apply to this trial

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

Apply to this trial

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

35 locations incl. California City

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

76 locations incl. Mesa

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting

Apply to this trial

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

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Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

for Duchenne Muscular Dystrophy

25 locations incl. Phoenix

Sponsor: Catalyst Pharmaceuticals, Inc.

Sex: Male·Age: 2+

Code: NCT06564974·Recruiting

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

Apply to this trial

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus of Childhood (Disorder)

6 locations incl. Birmingham

Sponsor: Michigan State University

Sex: All·Age: 12 - 22

Code: NCT06232304·Recruiting

Apply to this trial

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

Apply to this trial

A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

40 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting

Apply to this trial

Targeted Pediatric High-Grade Glioma Therapy

for High Grade Glioma

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05839379·Recruiting

Apply to this trial

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

for Differentiated Thyroid Cancer

4 locations incl. Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 25

Code: NCT06458036·Phase 2·Recruiting

Apply to this trial

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

13 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting

Apply to this trial

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

Apply to this trial

KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure

for Pediatric Intestinal Failure

8 locations incl. Boston

Sponsor: SterileCare Inc.

Sex: All·Age: 4 Weeks - 18

Code: NCT05879835·Recruiting

Apply to this trial

Spastic Paraplegia - Centers of Excellence Research Network

for Hereditary Spastic Paraplegia

11 locations incl. Miami

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06553976·Recruiting

Apply to this trial

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

for Inflammatory Bowel Diseases

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 6 - 21

Code: NCT06315179·Recruiting

Apply to this trial

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

for Duchenne Muscular Dystrophy

12 locations incl. Little Rock

Sponsor: Solid Biosciences Inc.

Sex: Male·Age: 0 - 17

Code: NCT06138639·Phase 1, Phase 2·Recruiting

Apply to this trial

Book Sharing for Toddlers With Clefts

for Cleft Palate

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 20 Months - 32 Months

Code: NCT06338319·Enrolling By Invitation

Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

for Pancreatitis

1 location in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06386224·Recruiting

Apply to this trial