Targeted Pediatric High-Grade Glioma Therapy

Part of paid clinical trials in Aurora, Colorado.

Sponsor
Nationwide Children's Hospital
Study ID
NCT05839379
Status
Recruiting
Apply to this trial

Conditions

  • Anaplastic Astrocytoma
  • Diffuse Intrinsic Pontine Glioma
  • Diffuse Midline Glioma, H3 K27M-Mutant
  • Glioblastoma
  • Glioblastoma Multiforme
  • High Grade Glioma
  • Metastatic Brain Tumor
  • WHO Grade III Glioma
  • WHO Grade IV Glioma

Eligibility Criteria

Sex
ALL
Age
12 Months - 39 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical trial based on the genetic alterations identified in their tumor.

Key Dates

Start date
Aug 2, 2024
Status verified
Sep 2025
Primary completion
Aug 28, 2029
Completion
Aug 28, 2034

Study Design

Enrollment
350 participants (estimated)

Primary Outcome Measure

Molecular profiling [ Time Frame: 4 years ]

Central Contacts

Locations (11)

FacilityCityStateZIPSite coordinators
Children's Hospital ColoradoAuroraColorado80045
Holly Lindsay, MD
[email protected]
720-777-8314
Children's National Medical CenterWashington D.C.District of Columbia20010
Eugene M Hwang, MD
[email protected]
2024765046
Ann & Robert H. Lurie Children's Hospital of ChicagoChicagoIllinois60611
Ashley Plant, MD
[email protected]
3122274090
Dana-Farber Cancer InstituteBostonMassachusetts02215
Susan C Chi, MD
[email protected]
6176324386
C.S. Mott Children's HospitalAnn ArborMichigan48109
Santhosh Upadhyaya, MD
[email protected]
866-909-4449
Duke University Health SystemDurhamNorth Carolina27708
Daniel Landi, MD
[email protected]
19196813824
Cincinnati Children's Hospital Medical CenterCincinnatiOhio45229
Peter M de Blank, MD
[email protected]
5135172068
Nationwide Children's HospitalColumbusOhio43205
Maryam Fouladi
[email protected]
6147225758
Children's Hospital of PhiladelphiaPhiladelphiaPennsylvania19104
Michael J Fisher, MD
[email protected]
12155905188
Texas Children's HospitalHoustonTexas77030
Patricia Baxter, MD
[email protected]
8328244681
Seattle Children's HospitalSeattleWashington98105
Erin Crotty, MD
[email protected]
206-987-2106

Find similar trials in Aurora, CO

By condition
Brain cancer
By specialty
OncologyNeuro-oncology
By research site
Children's Hospital Colorado· Aurora, COChildren's National Medical Center· Washington D.C., DCAnn & Robert H. Lurie Children's Hospital of Chicago· Chicago, ILDana-Farber Cancer Institute· Boston, MAC.S. Mott Children's Hospital· Ann Arbor, MIDuke University Health System· Durham, NC

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