An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Genefor Stargardt14 locations incl. San DiegoSponsor: Splice BioSex: All·Age: 12 - 65Code: NCT06435000·RecruitingApply to this trial
A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)for Chronic Myeloid Leukemia, Chronic Phase18 locations incl. BirminghamSponsor: Terns, Inc.Sex: All·Age: 18+Code: NCT06163430·Phase 1, Phase 2·RecruitingApply to this trial
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registryfor Cesarean Delivery34 locations incl. Little RockSponsor: Yale UniversitySex: Female·Age: 15 - 55·Accepts healthy volunteersCode: NCT06030063·RecruitingApply to this trial
A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CFfor Cystic Fibrosis13 locations incl. BirminghamSponsor: ReCode TherapeuticsSex: All·Age: 18 - 60·Accepts healthy volunteersCode: NCT06237335·Phase 2·RecruitingApply to this trial
A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)for Phenylketonuria (PKU)11 locations incl. AuroraSponsor: BioMarin PharmaceuticalSex: All·Age: All agesCode: NCT06305234·RecruitingApply to this trial
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)for Attention Deficit/Hyperactivity Disorder1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 6 - 17Code: NCT06133231·RecruitingApply to this trial
Sleep and Metabolismfor Sleep Deprivation1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 40·Accepts healthy volunteersCode: NCT05775627·RecruitingApply to this trial
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screeningfor Lung Cancer Diagnosis36 locations incl. Los AngelesSponsor: Freenome Holdings Inc.Sex: All·Age: 50+Code: NCT06122077·RecruitingApply to this trial
Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathyfor Radiation Retinopathy23 locations incl. Palo AltoSponsor: Jaeb Center for Health ResearchSex: All·Age: 18+Code: NCT05844982·Phase 3·RecruitingApply to this trial
Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMDfor Neovascular Age-related Macular Degeneration63 locations incl. GlendaleSponsor: Jaeb Center for Health ResearchSex: All·Age: 50+Code: NCT05904028·Phase 3·RecruitingApply to this trial
Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Agefor Lymphatic Malformation10 locations incl. BirminghamSponsor: Protara TherapeuticsSex: All·Age: 6 Months - 18Code: NCT05871970·Phase 2·RecruitingApply to this trial
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEmentfor Tricuspid Regurgitation5 locations incl. PhoenixSponsor: Montefiore Medical CenterSex: All·Age: 18+Code: NCT06033274·RecruitingApply to this trial
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignanciesfor GIST11 locations incl. Los AngelesSponsor: Deciphera Pharmaceuticals, LLCSex: All·Age: 18+Code: NCT05957367·Phase 1, Phase 2·RecruitingApply to this trial
Left vs Left Randomized Clinical Trialfor Heart Failure57 locations incl. GilbertSponsor: Baylor College of MedicineSex: All·Age: 18+Code: NCT05650658·RecruitingApply to this trial
First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumorsfor Advanced Solid Tumor6 locations incl. SarasotaSponsor: Daiichi SankyoSex: All·Age: 18+Code: NCT05875168·Phase 1, Phase 2·RecruitingApply to this trial
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Studyfor Neurocognitive Disorders1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 70 - 110·Accepts healthy volunteersCode: NCT06036095·Phase 4·RecruitingApply to this trial
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCMfor Hypertrophic Cardiomyopathy10 locations incl. La JollaSponsor: Tenaya TherapeuticsSex: All·Age: 18 - 75Code: NCT05836259·Phase 1, Phase 2·RecruitingApply to this trial
Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccinationfor Yellow Fever1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 20 - 49·Accepts healthy volunteersCode: NCT05859490·Phase 1, Phase 2·RecruitingApply to this trial
Peer Support Groups for Families With an Infant in the NICUfor Anxiety1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 70·Accepts healthy volunteersCode: NCT05988996·Enrolling By Invitation
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapyfor Pulmonary Embolism40 locations incl. BirminghamSponsor: NYU Langone HealthSex: All·Age: 18+Code: NCT05591118·Phase 3·RecruitingApply to this trial
NIBP Validation Studyfor Critical Illness5 locations incl. JacksonvilleSponsor: Philips Clinical & Medical Affairs GlobalSex: All·Age: All agesCode: NCT05673408·RecruitingApply to this trial
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignanciesfor Relapsed/Refractory B-cell Malignancies9 locations incl. DenverSponsor: Accutar Biotechnology IncSex: All·Age: 18+Code: NCT05780034·Phase 1·RecruitingApply to this trial
Alzheimer's Disease Neuroimaging Initiative 4for Mild Cognitive Impairment59 locations incl. BirminghamSponsor: University of Southern CaliforniaSex: All·Age: 55 - 90·Accepts healthy volunteersCode: NCT05617014·Enrolling By Invitation
Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healingfor Meniscus Tear3 locations incl. CincinnatiSponsor: University of CincinnatiSex: All·Age: 18 - 40Code: NCT05560477·Phase 1, Phase 2·RecruitingApply to this trial
Focus Groups in Ethnically and Racially Diverse Familiesfor Attention Deficit/Hyperactivity Disorder1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 80·Accepts healthy volunteersCode: NCT05930886·RecruitingApply to this trial
Fetoscopic Neural Tube Defect Repairfor Neural Tube Defects1 location in PortlandSponsor: Oregon Health and Science UniversitySex: Female·Age: 18+Code: NCT06946563·RecruitingApply to this trial
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignanciesfor Solid Tumor, Adult13 locations incl. Los AngelesSponsor: GV20 TherapeuticsSex: All·Age: 18+Code: NCT05669430·Phase 1, Phase 2·RecruitingApply to this trial
RSA Vs RCR for Massive RCTsfor Rotator Cuff Tears1 location in PortlandSponsor: La Tour HospitalSex: All·Age: 60 - 80Code: NCT05807854·RecruitingApply to this trial
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Informationfor Adult Growth Hormone Deficiency29 locations incl. PhoenixSponsor: Novo Nordisk A/SSex: All·Age: 18+Code: NCT05718570·Enrolling By Invitation
Descemet Endothelial Thickness Comparison Trial IIfor Fuchs8 locations incl. Palo AltoSponsor: Stanford UniversitySex: All·Age: 18+Code: NCT05275972·Phase 3·RecruitingApply to this trial
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosisfor Amyloidosis1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 40 - 90Code: NCT05758493·Phase 2·RecruitingApply to this trial
AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)for Duchenne Muscular Dystrophy13 locations incl. Little RockSponsor: REGENXBIO Inc.Sex: Male·Age: 1+Code: NCT05693142·Phase 2, Phase 3·RecruitingApply to this trial
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstructionfor Patellar Dislocation, Recurrent16 locations incl. Redwood CitySponsor: Hospital for Special Surgery, New YorkSex: All·Age: 10 - 35Code: NCT06883396·RecruitingApply to this trial
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)for Triple Negative Breast Cancer184 locations incl. BirminghamSponsor: Gilead SciencesSex: All·Age: 18+Code: NCT05633654·Phase 3·RecruitingApply to this trial
Safety and Target Engagement of Centella Asiatica in Cognitive Impairmentfor Mild Cognitive Impairment1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 60 - 85Code: NCT05591027·Phase 1·RecruitingApply to this trial
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)for Acute Myeloid Leukemia, in RelapseDrug: Iadademstat13 locations incl. GilbertSponsor: Oryzon Genomics S.A.Sex: All·Age: 18+Code: NCT05546580·Phase 1·RecruitingApply to this trial
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignanciesfor Hematologic Malignancy29 locations incl. Los AngelesSponsor: Therapeutic Advances in Childhood Leukemia ConsortiumSex: All·Age: 1 - 21Code: NCT05476770·Phase 1·RecruitingApply to this trial
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infectionfor Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection22 locations incl. BirminghamSponsor: University of CalgarySex: All·Age: 9 Months - 21Code: NCT05219110·RecruitingApply to this trial
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetesfor Type2Diabetes36 locations incl. HuntsvilleSponsor: Brigham and Women's HospitalSex: All·Age: 40 - 80Code: NCT05390892·Phase 4·RecruitingApply to this trial
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumorsfor Advanced Solid Tumors16 locations incl. Los AngelesSponsor: ModernaTX, Inc.Sex: All·Age: 12+Code: NCT05533697·Phase 1, Phase 2·RecruitingApply to this trial