Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

for Advanced Solid Tumor

6 locations incl. Santa Monica

Sponsor: Senhwa Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04890613·Phase 1·Recruiting

Apply to this trial

SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

14 locations incl. Birmingham

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

28 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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Zinc Oxide Versus Petrolatum Following Skin Surgery

for Surgical Incision

1 location in Pittsburgh, PA

Sponsor: Melissa Pugliano-Mauro

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03561376·EARLY_Phase 1·Recruiting

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

5 locations incl. San Francisco

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting

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Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for Anatomic Stage 0 Breast Cancer AJCC v8

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 40+

Code: NCT04959474·Recruiting

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Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

10 locations incl. Little Rock

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting

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A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

for Adenovirus Infections

11 locations incl. Los Angeles

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT04706923·Phase 2·Recruiting

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Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

for Retinopathy of Prematurity

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04995341·Recruiting

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Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

A Study Evaluating Oral Eluxadoline Administered to Pediatric Participants With Irritable Bowel Syndrome With Diarrhea (IBS-D)

for Irritable Bowel Syndrome

6 locations incl. Corona

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT04880876·Phase 3·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

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X-linked Moesin Associated Immunodeficiency

for Immune Deficiency

3 locations incl. Bethesda

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Sex: Male·Age: 4 - 80

Code: NCT06278337·Recruiting

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting

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Continuous Glucose Monitoring in At-Risk Newborns

for Neonatal Hypoglycemia

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 1 Minute - 2 Weeks

Code: NCT04386005·Recruiting

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IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Fear of Recurrence and Stopping Immunotherapy

for Cognitive Behavioral Therapy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 21+

Code: NCT04761328·Recruiting

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Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

for Brain Structure

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04856410·Enrolling By Invitation

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

for Adult Spinal Deformity

12 locations incl. Phoenix

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04885244·Recruiting

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Zimmer Biomet Shoulder Arthroplasty PMCF

for Shoulder Fractures

12 locations incl. Irvine

Sponsor: Zimmer Biomet

Sex: All·Age: 20+

Code: NCT04984291·Recruiting

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A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

29 locations incl. Birmingham

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT04976322·Phase 3·Enrolling By Invitation

Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement

for Osteoarthritis, Knee

2 locations incl. Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 45 - 80

Code: NCT04732962·Recruiting

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GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

for Cystic Fibrosis

2 locations incl. Aurora

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04731272·Phase 2·Recruiting

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Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

8 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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Valved Graft PMCF Study

for Aortic Valve Disease

5 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT04754217·Recruiting

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CureDuchenne Link®: A Resource for Research

for Duchenne Muscular Dystrophy

10 locations incl. Little Rock

Sponsor: CureDuchenne

Sex: All·Age: 4 Weeks+

Code: NCT04972604·Recruiting

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Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

for Liver Diseases

18 locations incl. Los Angeles

Sponsor: European Foundation for Study of Chronic Liver Failure

Sex: All·Age: 18 - 80

Code: NCT04613921·Recruiting

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Oral Nutritional Optimization in Total Joint Arthroplasty

for Osteoarthritis

2 locations incl. New York

Sponsor: NYU Langone Health

Sex: All·Age: 55+

Code: NCT04210284·Recruiting

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

27 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

20 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting

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EyeConic: Qualification for Cone-Optogenetics

for Retinal Dystrophies

3 locations incl. San Francisco

Sponsor: Institute of Molecular and Clinical Ophthalmology Basel

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05294978·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

9 locations incl. Indianapolis

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

57 locations incl. Long Beach

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting

Apply to this trial