Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,663 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,663 clinical trials

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Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419803·Recruiting

Apply to this trial

Pilot Trial of the RUBI Program for Autistic Adults

for Autism Spectrum Disorder

3 locations incl. Jupiter

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06593613·Recruiting

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Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

for Craniocerebral Trauma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06632587·Recruiting

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Taking Action for College Students

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06700902·Recruiting

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CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

5 locations incl. Santa Monica

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting

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MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers

for Breastfeeding, Exclusive

3 locations incl. Farmington

Sponsor: Benten Technologies, Inc.

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT06520696·Not Yet Recruiting

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

41 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

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A Study of Bleeding and Treatment in Participants With Von Willebrand Disease

for Von Willebrand Disease (VWD)

13 locations incl. Phoenix

Sponsor: Hemab ApS

Sex: All·Age: 16+

Code: NCT06610201·Recruiting

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KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

for Myasthenia Gravis

8 locations incl. Orange

Sponsor: Kyverna Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06193889·Phase 2, Phase 3·Recruiting

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Reducing Urban Cervical Cancer Disparities

for Cervical Cancer

3 locations incl. New Brunswick

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06416150·Recruiting

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A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Non-small Cell Lung Cancer, HER2 Mutation

27 locations incl. Newport Beach

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06452277·Phase 3·Recruiting

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First In Human Study of CX-801 in Advanced Solid Tumors

for Solid Tumor, Adult

3 locations incl. Englewood

Sponsor: CytomX Therapeutics

Sex: All·Age: 18+

Code: NCT06462794·Phase 1·Recruiting

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Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

7 locations incl. La Jolla

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting

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Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

for Diabetic Foot Ulcer

1 location in Monroeville

Sponsor: MiMedx Group, Inc.

Sex: All·Age: 18+

Code: NCT06600724·Recruiting

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The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

for Smoking

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06264154·Recruiting

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Exparel v Dexamethasone in RCR

for Rotator Cuff Tears

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06575010·Phase 4·Enrolling By Invitation

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Sacramento

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06352359·Phase 1·Recruiting

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Effects of Mindfulness and Yoga on Preschool Students' Emotional Regulation, Behavior, and Social Participation

for Prosocial Behavior

1 location in Elizabethtown

Sponsor: Elizabethtown College

Sex: All·Age: 4 - 6·Accepts healthy volunteers

Code: NCT06561373·Not Yet Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

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Letrozole and Misoprostol for Early Pregnancy Loss Management

for Early Pregnancy Loss

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06452719·Phase 2·Recruiting

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Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

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Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

6 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06535607·Phase 2·Recruiting

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A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

31 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting

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School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes

for Type 1 Diabetes

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 5 - 12

Code: NCT06420661·Enrolling By Invitation

Abbott Structural Heart Device Registry

for Heart Diseases

5 locations incl. New Brunswick

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT06590467·Recruiting

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EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment

for Ischemic Stroke

14 locations incl. Downey

Sponsor: BrainQ Technologies Ltd.

Sex: All·Age: 22 - 80

Code: NCT06386874·Recruiting

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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

for Acute HIV Infection

32 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT05719441·Phase 2·Recruiting

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Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)

for Necrotizing Enterocolitis

8 locations incl. Little Rock

Sponsor: Noveome Biotherapeutics, formerly Stemnion

Sex: All·Age: 2 Weeks - 8 Weeks

Code: NCT06315738·Phase 1, Phase 2·Recruiting

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Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

for Antiphospholipid Syndrome (APS)

11 locations incl. Orange

Sponsor: Chugai Pharmaceutical

Sex: All·Age: 18 - 85

Code: NCT06371417·Phase 1·Recruiting

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Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for B-cell Acute Lymphoblastic Leukemia

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 6 Months - 25

Code: NCT06395103·Phase 1, Phase 2·Recruiting

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Bone in CKD Alkali Response (BICARb Pilot Trial)

for Chronic Kidney Diseases

2 locations incl. The Bronx

Sponsor: Albert Einstein College of Medicine

Sex: All·Age: 5 - 100

Code: NCT05918029·Phase 2, Phase 3·Recruiting

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Nafamostat Efficacy in Phase 3 Registrational CRRT Study

for Acute Kidney Injury

10 locations incl. Los Angeles

Sponsor: Talphera, Inc

Sex: All·Age: 18 - 80

Code: NCT06150742·Recruiting

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Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)

for Hip Fractures

6 locations incl. Gainesville

Sponsor: University of Pennsylvania

Sex: All·Age: 50+

Code: NCT06438640·Recruiting

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The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial

for Endometriosis

1 location in Wynnewood

Sponsor: Main Line Health

Sex: Female·Age: 18+

Code: NCT06439524·Phase 3·Recruiting

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TumorGlow Intraoperative Molecular Imaging (IMI)

for Tumor, Solid

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04723810·Phase 1, Phase 2·Recruiting

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A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

for Muscular Atrophy, Spinal

10 locations incl. Little Rock

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Months - 24 Months

Code: NCT05861999·Phase 4·Recruiting

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Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

for Heart Failure

4 locations incl. Detroit

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06291922·Recruiting

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A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

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Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children

for Pediatric ALL

3 locations incl. New York

Sponsor: University of Pennsylvania

Sex: All·Age: 4 Weeks - 18

Code: NCT06529575·Recruiting

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MSC EVs in Dystrophic Epidermolysis Bullosa

for Dystrophic Epidermolysis Bullosa

3 locations incl. Phoenix

Sponsor: Aegle Therapeutics

Sex: All·Age: 6 Months+

Code: NCT04173650·Phase 1, Phase 2·Recruiting

Apply to this trial