Non-small cell lung cancer (NSCLC) Clinical Trials in Orange City, FL
As of June 2026, 14 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Orange City, Florida. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Orange City
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14 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·↓ Download CSVBeamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
About research studies in Orange City
Orange City has approximately 58 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Orange City
Researchers run research studies in Orange City, FL at 24 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mid Florida Hematology and Oncology Center | Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung (NSCLC) | 21 |
| Medical Research Group of Central Florida | Attention-Deficit/Hyperactivity Disorder, Depression, Major Depressive Disorder (MDD) | 5 |
| Optimal Research Sites | Depressive Disorder, Major, Diabetes Mellitus, Type 2, Idiopathic Short Stature | 3 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
| Gastroenterology of Greater Orlando | Cancer, Eosinophilic Esophagitis (EoE) | 2 |
| Hillcrest Medical Research | Bowel; Stricture, Esophageal Stricture | 2 |
| Kailera Clinical Site | Obesity, Obesity With Diabetes, Overweight With Diabetes | 2 |
| Mid-Florida Hematology & Oncology Centers, P.A. | Non-small Cell Lung Cancer, Patients With Chemotherapy-Induced Thrombocytopenia | 2 |
| Neurocrine Clinical Site | Tardive Dyskinesia, Bipolar Disorder, Major Depressive Disorder | 2 |
| Florida Cancer Specialists - North | Limited Stage Small Cell Lung Cancer | 1 |
| Florida Cancer Specialists North / Sarah Cannon Research Institute | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Florida Hospital FISH | Anal Cancer, Bile Duct Cancer, Bladder Cancer | 1 |
| Harmony Clinical Research - Orlando | Chronic Idiopathic Constipation (CIC) | 1 |
| Hillcrest Medical Research, LLC | Crohn's Disease | 1 |
| Local Institution - 0023 | Schizophrenia | 1 |
| Local Institution - 124 | Schizophrenia | 1 |
| Mid Florida Cancer Centers | Non-small Cell Lung Cancer | 1 |
| Mid Florida Center | Advanced Solid Tumors | 1 |
| Mid Florida Hematology and Oncology Centers | Cancer-associated Cachexia | 1 |
| Mid Florida Hematology and Oncology Centers PA | Metastatic Colorectal Cancer | 1 |
| Mid-Florida Hematology Oncology | Limited-stage Small Cell Lung Cancer (LS-SCLC) | 1 |
| Midland Florida Clinical Research Center, L | Triple Negative Breast Cancer | 1 |
| The Clinical Trials Network CTNX LLC | Crohn's Disease, Ulcerative Colitis | 1 |
| Zai Lab | Small-cell Lung Cancer | 1 |
Active & Upcoming Studies in Orange City (2026)
Recruiting trials in Orange City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (33 active studies)
- Visugromab in Cachexia International Trial · Phase 2, Phase 3 · CatalYm GmbH
- Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers · Phase 1, Phase 2 · Pfizer
Mental health & behavior (5 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT) · Bristol-Myers Squibb
Diabetes & metabolic (3 active studies)
- AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes · Phase 3 · Kailera
Neurology & pain (2 active studies)
- Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17) · Phase 3 · AbbVie
- Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17) · Phase 3 · AbbVie
Common conditions studied in Orange City
- Non-small Cell Lung Cancer (8 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Non-Small Cell Lung Cancer (4 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Carcinoma, Non-Small-Cell Lung (3 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Schizophrenia (3 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Advanced Solid Tumors (2 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Bladder Cancer (2 active studies). Recruiting Bladder Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Orange City
- AbbVie
- Pfizer
- Merck Sharp & Dohme LLC
- AstraZeneca
- Bristol-Myers Squibb
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Orange City. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Orange City
Hipa.ai aggregates every recruiting study in Orange City from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange City?
There are approximately 58 recruiting clinical trials in Orange City, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange City pay participants?
Most recruiting trials in Orange City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange City?
The most common conditions under active study in Orange City include Non-small Cell Lung Cancer (8), Non-Small Cell Lung Cancer (4), Carcinoma, Non-Small-Cell Lung (3), Schizophrenia (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange City?
Recruiting research sites in Orange City include Mid Florida Hematology and Oncology Center, Medical Research Group of Central Florida, Optimal Research Sites, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange City right now?
The largest active categories in Orange City are Cancer & tumors (33), Mental health & behavior (5), Diabetes & metabolic (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.