Paid Clinical Trials in Oklahoma

Oklahoma has 836 paid clinical trials enrolling now across cities including Oklahoma City, Tulsa and Edmond. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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836 clinical trials

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

59 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting

Apply to this trial

Ketogenic Diet in Rheumatoid Arthritis (RA)

for Rheumatoid Arthritis

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 65

Code: NCT05799768·Enrolling By Invitation

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

21 locations incl. Birmingham

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting

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Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

45 locations incl. Tuscaloosa

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting

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Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for Recurrent Glioblastoma, IDH-Wildtype

Drug: Selinexor

36 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05432804·Phase 1, Phase 2·Recruiting

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

175 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

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Investigation of DEXA-C Anterior Cervical Interbody System

for Degenerative Disc Disease

4 locations incl. Orange

Sponsor: Aurora Spine and Pain

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05883436·Recruiting

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

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Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

Drug: IMNN-001

4 locations incl. Baltimore

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT05739981·Phase 1, Phase 2·Recruiting

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A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

for Endometrioid Cancer

Drug: Avutometinib

4 locations incl. Orlando

Sponsor: University of Oklahoma

Sex: Female·Age: 18 - 99

Code: NCT05512208·Phase 2·Recruiting

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Oklahoma Study of Native American Pain Risk III: Stress and Resilience

for Discrimination, Racial

1 location in Tulsa

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05723081·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

785 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting

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Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

3 locations incl. Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18 - 70

Code: NCT05256641·Phase 1, Phase 2·Recruiting

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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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Pilot Imaging Study of Leukemia

for Acute Lymphocytic Leukemia

3 locations incl. Washington D.C.

Sponsor: University of Oklahoma

Sex: All·Age: 4 - 80

Code: NCT03633955·Phase 1·Recruiting

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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

12 locations incl. New Haven

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

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A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

18 locations incl. Loma Linda

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05592626·Phase 1, Phase 2·Recruiting

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

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A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination

for Advanced Solid Tumor

3 locations incl. Sarasota

Sponsor: Selecxine

Sex: All·Age: 18+

Code: NCT05525247·Phase 1, Phase 2·Recruiting

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Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

for High-Risk Percutaneous Coronary Intervention

32 locations incl. Phoenix

Sponsor: Abiomed Inc.

Sex: All·Age: 18 - 90

Code: NCT05334784·Enrolling By Invitation

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

68 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting

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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

68 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

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Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for High Grade Epithelial Ovarian Cancer

37 locations incl. Phoenix

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05579366·Phase 1, Phase 2·Recruiting

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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

55 locations incl. Washington D.C.

Sponsor: NRG Oncology

Sex: Female·Age: 18+

Code: NCT05646316·Phase 3·Recruiting

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BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for Clinical Stage III Cutaneous Melanoma AJCC v8

Drug: Cabozantinib

222 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05136196·Phase 2·Recruiting

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Combined Electric and Acoustic Hearing (EAS) in Children and Adults

for Cochlear Implant

4 locations incl. Edmond

Sponsor: Hearts for Hearing

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT05923203·Recruiting

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Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

for Advanced Malignant Solid Neoplasm

3 locations incl. New Haven

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05053971·Phase 1, Phase 2·Recruiting

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

Apply to this trial

The Oklahoma Parent-Child Assistance Program

for Substance Use Disorders

2 locations incl. Oklahoma City

Sponsor: University of Oklahoma

Sex: Female·Age: 18+

Code: NCT05534568·Recruiting

Apply to this trial

Behavioral Activation + Occupational Therapy: An Innovative Intervention for Empowered Self-Management of Multiple Chronic Conditions

for Multiple Chronic Conditions

1 location in Tulsa

Sponsor: University of Oklahoma

Sex: All·Age: 60+

Code: NCT05600465·Recruiting

Apply to this trial

Muscle Recovery After Critical Illness

for ICU Acquired Weakness

3 locations incl. Birmingham

Sponsor: Kirby Mayer

Sex: Male·Age: 18+

Code: NCT05537298·Recruiting

Apply to this trial