Paid Clinical Trials in Ohio

Ohio has 3,476 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,477 clinical trials

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A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Non-small Cell Lung Cancer, HER2 Mutation

27 locations incl. Newport Beach

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06452277·Phase 3·Recruiting

Apply to this trial

Optimal Duration of Foley Catheter After Bulbar Urethroplasty

for Urethral Stricture, Bulbar

4 locations incl. Burlington

Sponsor: Jane Kurtzman

Sex: Male·Age: 18 - 70

Code: NCT07220980·Enrolling By Invitation

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

for Multiple Myeloma

9 locations incl. San Francisco

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06500884·Phase 2·Recruiting

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QL Block in Laparoscopic Myomectomy

for Postoperative Pain

1 location in Beachwood

Sponsor: Joseph Findley MD

Sex: Female·Age: 18 - 45

Code: NCT05979493·Phase 4·Recruiting

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

4 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting

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A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

for Multiple Myeloma

50 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT06413498·Phase 3·Recruiting

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Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

for Parkinson Disease

1 location in Cleveland

Sponsor: Jay Alberts

Sex: All·Age: 18+

Code: NCT06442033·Recruiting

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

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Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

6 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06535607·Phase 2·Recruiting

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Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

for Acquired Antithrombin Deficiency

9 locations incl. Stanford

Sponsor: Octapharma

Sex: All·Age: 18 - 85

Code: NCT06096116·Phase 3·Recruiting

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A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

31 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting

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Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

for Diet, Food and Nutrition

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 60+

Code: NCT06586970·Recruiting

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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

for Acute HIV Infection

32 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT05719441·Phase 2·Recruiting

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Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

for Antiphospholipid Syndrome (APS)

11 locations incl. Orange

Sponsor: Chugai Pharmaceutical

Sex: All·Age: 18 - 85

Code: NCT06371417·Phase 1·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: Upadacitinib

30 locations incl. Little Rock

Sponsor: AbbVie

Sex: All·Age: 2 - 11

Code: NCT06461897·Phase 3·Recruiting

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A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers

for Diabetic Foot Ulcer

1 location in Clevland

Sponsor: Organogenesis

Sex: All·Age: 18+

Code: NCT06618612·Recruiting

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Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

for Somatic Mutation

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06357845·Recruiting

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Nafamostat Efficacy in Phase 3 Registrational CRRT Study

for Acute Kidney Injury

10 locations incl. Los Angeles

Sponsor: Talphera, Inc

Sex: All·Age: 18 - 80

Code: NCT06150742·Recruiting

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Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)

for Hip Fractures

6 locations incl. Gainesville

Sponsor: University of Pennsylvania

Sex: All·Age: 50+

Code: NCT06438640·Recruiting

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Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

for Heart Failure

4 locations incl. Detroit

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06291922·Recruiting

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A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

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SMP-3124LP in Adults With Advanced Solid Tumors

for Solid Tumor

8 locations incl. Los Angeles

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06526819·Phase 1, Phase 2·Recruiting

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Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

for Advanced Solid Tumor

10 locations incl. Sarasota

Sponsor: Circle Pharma

Sex: All·Age: 12+

Code: NCT06577987·Phase 1·Recruiting

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EFS of the DUO System for Tricuspid Regurgitation

for Tricuspid Regurgitation

12 locations incl. Phoenix

Sponsor: CroiValve Limited

Sex: All·Age: 18+

Code: NCT05913908·Recruiting

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A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for Metastatic HER2-positive Breast Cancer

48 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06435429·Phase 3·Recruiting

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Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer

for Prostate Adenocarcinoma

Drug: Relugolix

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Male·Age: 18+

Code: NCT06330805·Phase 2·Recruiting

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NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

for Elbow Pain

2 locations incl. Coral Springs

Sponsor: The Cleveland Clinic

Sex: All·Age: 18 - 65

Code: NCT06373978·Phase 4·Recruiting

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Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for Biliary Tract Cancer

Drug: Rilvegostomig

48 locations incl. Scottsdale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT06467357·Phase 3·Recruiting

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Melodi Matrix™ in Breast Reconstruction

for Breast Reconstruction

10 locations incl. Palo Alto

Sponsor: Melodi Health, Inc.

Sex: Female·Age: 22+

Code: NCT06027996·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

266 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting

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A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

40 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

12 locations incl. Oakland

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT06332534·Phase 3·Recruiting

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Evaluation of Music Therapy for Pre-op/Intra-op During Hernia Surgery to Decrease the Need for Narcotics

for Surgery

1 location in Cincinnati

Sponsor: TriHealth Inc.

Sex: All·Age: 18+

Code: NCT06957990·Enrolling By Invitation

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)

for Relapsed/Refractory Systemic Light Chain Amyloidosis

Drug: Linvoseltamab

7 locations incl. Duarte

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06292780·Phase 1, Phase 2·Recruiting

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Kerecis Real-World Fish Skin Graft Registry

for Wounds

6 locations incl. Sarasota

Sponsor: Kerecis Ltd.

Sex: All·Age: All ages

Code: NCT06384183·Enrolling By Invitation

A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

51 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting

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Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

for Non Small Cell Lung Cancer

Drug: Adagrasib

3 locations incl. Columbus

Sponsor: Ryan Gentzler, MD

Sex: All·Age: 18+

Code: NCT06248606·Phase 2·Recruiting

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Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for PSMA PET-Positive Castration-Resistant Prostate Cancer

9 locations incl. San Diego

Sponsor: Convergent Therapeutics

Sex: Male·Age: 18+

Code: NCT06549465·Phase 2·Recruiting

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Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

for Tricuspid Regurgitation

9 locations incl. Thousand Oaks

Sponsor: Innoventric LTD

Sex: All·Age: 18 - 85

Code: NCT06212193·Recruiting

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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

32 locations incl. Tucson

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06428019·Phase 3·Recruiting

Apply to this trial