Clinical Trials at Mount Sinai Hospital

As of June 2026, 132 paid clinical trials are recruiting at Mount Sinai Hospital, located at 5 E 98TH ST, BOX 1188, NEW YORK, NY 10029-6501, phone (212) 241-1621 in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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132 clinical trials at Mount Sinai Hospital

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

256 locations incl. Tucson

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting

Apply to this trial

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

for Ventricular Ejection Fraction

8 locations incl. Orange

Sponsor: Peerbridge Health, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06699056·Recruiting

Apply to this trial

A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

for Carotid Artery Diseases

8 locations incl. Sacramento

Sponsor: InspireMD

Sex: All·Age: 18 - 79

Code: NCT06653387·Recruiting

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

29 locations incl. St. Helena

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting

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Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)

for Hypoxemia

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: Up to 18

Code: NCT06575270·Recruiting

Apply to this trial

SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery

for Frailty

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06704256·Recruiting

Apply to this trial

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

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Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting

Apply to this trial

Intrathecal Dexmedetomidine vs Epinephrine

for Cesarean Section

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 18 - 55

Code: NCT06418308·Phase 4·Recruiting

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

167 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting

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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

24 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting

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Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

for Acute Ischemic Stroke From Large Vessel Occlusion

11 locations incl. Jacksonville

Sponsor: Anaconda Biomed S.L.

Sex: All·Age: 22 - 85

Code: NCT06370182·Recruiting

Apply to this trial

Abbott Structural Heart Device Registry

for Heart Diseases

5 locations incl. New Brunswick

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT06590467·Recruiting

Apply to this trial

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for Head and Neck Squamous Cell Carcinoma

29 locations incl. Duarte

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06163534·Recruiting

Apply to this trial

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

for Bladder Cancer

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06689176·Recruiting

Apply to this trial

A Prospective Research Investigation of Ischemia Using MCG

for Acute Coronary Syndrome

2 locations incl. Rochester

Sponsor: SB Technology, Inc.

Sex: All·Age: 18+

Code: NCT06481943·Recruiting

Apply to this trial

Neurosteer Bedside Monitoring System

for Delirium

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06718764·Recruiting

Apply to this trial

Different Medications to Induce Labor

for Pregnancy

2 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 18+

Code: NCT06259097·Phase 3·Recruiting

Apply to this trial

USCOM in Newly Diagnosed FGR Cases

for Fetal Growth Restriction

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06343051·Recruiting

Apply to this trial

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

51 locations incl. Mobile

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting

Apply to this trial

Investigation of a 3 oz Water Protocol on Patients With Tracheostomies

for Tracheostomy

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06120790·Recruiting

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Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer

for Metastatic Breast Cancer

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 18+

Code: NCT06405828·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

104 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

Apply to this trial

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

for Aortic Valve Stenosis

67 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05932615·Enrolling By Invitation

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

490 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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AMPK-activation by Metformin in FSGS: AMP-FSGS

for Focal Segmental Glomerulosclerosis

2 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 80

Code: NCT06090227·Phase 1, Phase 2·Recruiting

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Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF

for Atrial Fibrillation

6 locations incl. Jonesboro

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 80

Code: NCT06099730·Recruiting

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ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients

for Paroxysmal Atrial Fibrillation

8 locations incl. Jonesboro

Sponsor: Vivek Reddy

Sex: All·Age: 18+

Code: NCT05988411·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

536 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

Apply to this trial

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

for Prostate Cancer

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Male·Age: 18+

Code: NCT06945315·Phase 3·Recruiting

Apply to this trial

Trial of Ixazomib for Kaposi Sarcoma

for Kaposi Sarcoma

11 locations incl. San Diego

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04305691·Phase 2·Recruiting

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

60 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting

Apply to this trial

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

for Metastatic Colorectal Adenocarcinoma

184 locations incl. Kingman

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05673148·Phase 3·Recruiting

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HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

for Erythropoietic Protoporphyria

11 locations incl. Birmingham

Sponsor: Disc Medicine, Inc

Sex: All·Age: 12+

Code: NCT05883748·Phase 2, Phase 3·Enrolling By Invitation

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

Apply to this trial

Pembrolizumab for Advanced NSCLC and PS 2-3

for Non-Small Cell Lung Cancer (NSCLC)

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT05589818·Phase 2·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

Apply to this trial

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

for Anal Carcinoma

8 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05663502·Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

Apply to this trial