Clinical Trials at Columbia University Medical Center

As of June 2026, 136 paid clinical trials are recruiting at Columbia University Medical Center, located at 630 W 168TH ST, NEW YORK, NY 10032-3725, phone (212) 305-5084 in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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136 clinical trials at Columbia University Medical Center

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A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

for Sickle Cell Disease

16 locations incl. Oakland

Sponsor: Editas Medicine, Inc.

Sex: All·Age: 12 - 50

Code: NCT06363760·Enrolling By Invitation

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

Drug: Nivolumab

37 locations incl. Tucson

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting

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A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

for Muscular Atrophy, Spinal

11 locations incl. Little Rock

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Months - 24 Months

Code: NCT05861986·Phase 4·Recruiting

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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

32 locations incl. Chandler

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting

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PediRISE Feasibility

for Pediatric Cancer

4 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06283251·Recruiting

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

34 locations incl. Birmingham

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting

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A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

17 locations incl. San Francisco

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting

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Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

44 locations incl. Homewood

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

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An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene

for Stargardt

14 locations incl. San Diego

Sponsor: Splice Bio

Sex: All·Age: 12 - 65

Code: NCT06435000·Recruiting

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A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors

for Acute Lymphoblastic Leukemia

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 5 - 21

Code: NCT05963971·Recruiting

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A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Guselkumab

14 locations incl. Los Angeles

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2 - 17

Code: NCT05923073·Phase 3·Recruiting

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Primary Connections for Youth and Families

for Substance Use

1 location in New York

Sponsor: The National Center on Addiction and Substance Abuse at Columbia University

Sex: All·Age: 12 - 17·Accepts healthy volunteers

Code: NCT05964010·Recruiting

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Gadopiclenol in Contrast Enhanced MRI of the Prostate

for Prostate Cancer

1 location in New York

Sponsor: Columbia University

Sex: Male·Age: 18+

Code: NCT06226129·Phase 4·Recruiting

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Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for Non-Small Cell Lung Cancer, NSCLC

26 locations incl. Gilbert

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06162221·Phase 1, Phase 2·Recruiting

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Kids With Iron Deficiency and Scoliosis

for Adolescent Idiopathic Scoliosis

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 10 - 26·Accepts healthy volunteers

Code: NCT06042699·Recruiting

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A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

for Hemolytic Disease of the Fetus and Newborn

Drug: Nipocalimab

18 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT05912517·Phase 3·Recruiting

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

38 locations incl. Tucson

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting

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A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

for Adenocarcinoma, Pancreatic Ductal

Drug: Atezolizumab

32 locations incl. Los Angeles

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT05968326·Phase 2·Recruiting

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CTSN Embolic Protection Trial

for Delirium

24 locations incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

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Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

for Breast Cancer

3 locations incl. New York

Sponsor: University Health Network, Toronto

Sex: Female·Age: 18 - 99

Code: NCT05592938·Recruiting

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Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

for Crohn Disease

22 locations incl. Phoenix

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 6 - 17

Code: NCT05781152·Phase 4·Recruiting

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Weight Loss Study: Genetics and Response to Naltrexone/Bupropion

for Obesity

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 65

Code: NCT05919797·Phase 4·Recruiting

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

40 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

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IMPACT Trial: Intervention to iMProve AdherenCe Equitably

for Breast Cancer

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 99

Code: NCT05496829·Recruiting

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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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Continuation of the nuMoM2b Heart Health Study

for Cardiovascular Diseases

14 locations incl. Orange

Sponsor: RTI International

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05472597·Enrolling By Invitation

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

for Amyloidosis, Hereditary

3 locations incl. New York

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 30 - 80

Code: NCT05489549·Recruiting

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EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

for Heart Failure

15 locations incl. Los Angeles

Sponsor: Berlin Heart, Inc

Sex: All·Age: Up to 21

Code: NCT05610787·Enrolling By Invitation

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

Enhanced Nutritional Optimization in LVAD Trial

for Heart Failure

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT05655910·Recruiting

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A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

61 locations incl. Anniston

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05531565·Phase 2, Phase 3·Recruiting

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Outcome of Patients With Severe Functional TR According to Medical, Transcatheter or Surgical Treatment

for Tricuspid Regurgitation

4 locations incl. Rochester

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT05825898·Enrolling By Invitation

Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

for Pancreatic Cancer Metastatic

14 locations incl. Hot Springs

Sponsor: Panbela Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05254171·Phase 2, Phase 3·Recruiting

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ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study

for Age Related Macular Degeneration (AMD)

22 locations incl. Poway

Sponsor: Gyroscope Therapeutics Limited

Sex: All·Age: 55+

Code: NCT05481827·Phase 2·Enrolling By Invitation

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

for Colitis, Ulcerative

36 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 2 - 17

Code: NCT05076175·Phase 2, Phase 3·Recruiting

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

19 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting

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