Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

Apply to this trial

The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study

for Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05464095·Recruiting

Apply to this trial

PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

30 locations incl. La Jolla

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting

Apply to this trial

Metastatic Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

9 locations incl. Santa Monica

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT05653388·Recruiting

Apply to this trial

Combined Electric and Acoustic Hearing (EAS) in Children and Adults

for Cochlear Implant

4 locations incl. Edmond

Sponsor: Hearts for Hearing

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT05923203·Recruiting

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A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for Pediatric Sarcoma, Refractory

22 locations incl. South Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 2 - 40

Code: NCT05634369·Phase 1, Phase 2·Recruiting

Apply to this trial

MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing

for C-section

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18 - 40

Code: NCT05505110·EARLY_Phase 1·Recruiting

Apply to this trial

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

for Immunization

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 16+

Code: NCT05215327·Phase 2·Recruiting

Apply to this trial

Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults

for Reading Disability

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05523505·Recruiting

Apply to this trial

Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA

for Obstructive Sleep Apnea

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05501236·Recruiting

Apply to this trial

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

for Idiopathic Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 15 - 80

Code: NCT05584722·Recruiting

Apply to this trial

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for Atherosclerotic Cardiovascular Disease in Patients With ESKD

Drug: Clazakizumab

164 locations incl. Decatur

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT05485961·Phase 2, Phase 3·Recruiting

Apply to this trial

Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)

for Asthma

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05254314·Phase 2·Recruiting

Apply to this trial

Met Non Small Cell Cancer Registry (MOMENT)

for Cancer

3 locations incl. Fort Lauderdale

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: All ages

Code: NCT05376891·Recruiting

Apply to this trial

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

for Cognitive Rehabilitation

2 locations incl. Nashville

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04353804·Recruiting

Apply to this trial

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

61 locations incl. Anniston

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05531565·Phase 2, Phase 3·Recruiting

Apply to this trial

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

TVMR With the INNOVALVE System Trial - Early Feasibility Study

for Mitral Valve Regurgitation (Degenerative or Functional)

20 locations incl. Los Angeles

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04919980·Recruiting

Apply to this trial

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for HR+/HER2-negative Breast Cancer

10 locations incl. Loma Linda

Sponsor: SynDevRx, Inc.

Sex: All·Age: 18+

Code: NCT05455619·Phase 1, Phase 2·Recruiting

Apply to this trial

Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

4 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting

Apply to this trial

Cooperative Assessment of Late Effects for SCD Curative Therapies

for Sickle Cell Disease

5 locations incl. Washington D.C.

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 4 - 65

Code: NCT05153967·Recruiting

Apply to this trial

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

for Amyloid Plaque

13 locations incl. Phoenix

Sponsor: AC Immune SA

Sex: All·Age: 35 - 85

Code: NCT05462106·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of ASP3082 in Adults With Advanced Solid Tumors

for Solid Tumor

23 locations incl. Duarte

Sponsor: Astellas Pharma Inc

Sex: All·Age: 18+

Code: NCT05382559·Phase 1·Recruiting

Apply to this trial

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

for Post-acute COVID-19 Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05421208·Recruiting

Apply to this trial

Cabozantinib for Patients With Recurrent or Progressive Meningioma

for Meningioma

Drug: Cabozantinib

3 locations incl. Miami

Sponsor: Baptist Health South Florida

Sex: All·Age: 18+

Code: NCT05425004·Phase 2·Recruiting

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

19 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting

Apply to this trial

The CONFORM Pivotal Trial

for Atrial Fibrillation

76 locations incl. Birmingham

Sponsor: Conformal Medical, Inc

Sex: All·Age: 18+

Code: NCT05147792·Recruiting

Apply to this trial

Sympathetic Mechanisms in Obesity-Crossover Design

for Obesity

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT05312892·Phase 1, Phase 2·Recruiting

Apply to this trial

SELUTION4BTK Trial

for Peripheral Arterial Disease

30 locations incl. Chandler

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05055297·Recruiting

Apply to this trial

Posterior Cervical Fixation Study

for Degenerative Disc Disease

7 locations incl. Orange

Sponsor: NuVasive

Sex: All·Age: 18+

Code: NCT04770571·Enrolling By Invitation

Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass

for Congenital Heart Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 0 - 1

Code: NCT05101746·Phase 2, Phase 3·Enrolling By Invitation

Use of CereGate Therapy for Freezing of Gait in PD

for Parkinson Disease

7 locations incl. Redwood City

Sponsor: CereGate Inc.

Sex: All·Age: 21 - 80

Code: NCT05292794·Recruiting

Apply to this trial

Effect of Ketamine and Etomidate During RSI on Long Term Outcomes

for Post-Traumatic Stress Disorder

6 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06179485·Enrolling By Invitation

Trisol System EFS Study

for Tricuspid Regurgitation

7 locations incl. Los Angeles

Sponsor: Trisol Medical

Sex: All·Age: 18+

Code: NCT04905017·Recruiting

Apply to this trial

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

for Opioid Use Disorder

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05142267·Recruiting

Apply to this trial

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

for Heart Failure

37 locations incl. Fairhope

Sponsor: Cordio Medical

Sex: All·Age: 22+

Code: NCT06378632·Recruiting

Apply to this trial

Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial

for Shoulder Dislocation

15 locations incl. Tempe

Sponsor: University of Pittsburgh

Sex: All·Age: 17 - 50

Code: NCT04809064·Recruiting

Apply to this trial

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

for Type 2 Diabetes Mellitus

79 locations incl. Huntsville

Sponsor: Prokidney

Sex: All·Age: 30 - 80

Code: NCT05099770·Phase 3·Recruiting

Apply to this trial

Extension Study of Infigratinib in Children With Achondroplasia (ACH)

for Achondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT05145010·Phase 2·Enrolling By Invitation