Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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Project VOICES: Vocal Optimization in Children Elevating the Spectrum

for Autism

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 2 - 5

Code: NCT06875843·Recruiting

Apply to this trial

An Interventional Study of Infigratinib in Children With Hypochondroplasia

for Hypochondroplasia

7 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT06873035·Phase 2, Phase 3·Enrolling By Invitation

Swallowing Impairments in Adults With and Without Alzheimer's Disease

for Alzheimer Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06678100·Recruiting

Apply to this trial

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

for HNSCC

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06819228·EARLY_Phase 1·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

Apply to this trial

Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction

for Wound Healing

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 22+

Code: NCT06634030·Phase 2·Recruiting

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BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for Non-Small Cell Lung Cancer

16 locations incl. Los Angeles

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06917079·Phase 1·Recruiting

Apply to this trial

The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

18 locations incl. Torrance

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

Apply to this trial

MObile Support Adapted to Individual Contexts

for Type 2 Diabetes

2 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT06828549·Enrolling By Invitation

A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma, Clear Cell

Drug: Ipilimumab

6 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06708949·Phase 2·Recruiting

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

Apply to this trial

Barriers and Facilitators to OTC Hearing Aids Success

for Hearing Loss, Sensorineural

2 locations incl. Iowa City

Sponsor: Yu-Hsiang Wu

Sex: All·Age: 18 - 89

Code: NCT06499805·Recruiting

Apply to this trial

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

for Type 2 Diabetes Mellitus (T2DM)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06852950·Recruiting

Apply to this trial

Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee

for Subchondral Insufficiency Fracture

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT06423378·Phase 2·Enrolling By Invitation

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

for Achondroplasia

11 locations incl. Torrance

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 3 - 10

Code: NCT06842355·Phase 2·Recruiting

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A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

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Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

for Orthopaedic Trauma

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06201676·Phase 4·Recruiting

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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

21 locations incl. Scottsdale

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting

Apply to this trial

Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

Apply to this trial

The Dose Trial: Dose Intensity of Behavioral Interventions for Childhood Obesity

for Childhood Obesity

2 locations incl. Baton Rouge

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 5 - 17

Code: NCT06654323·Recruiting

Apply to this trial

Exercise Testing After Preeclampsia

for Preeclampsia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06741436·Recruiting

Apply to this trial

Point-of-Care Ophthalmic Diagnostic Imaging of Retinopathy of Prematurity

for Retinopathy of Prematurity (ROP)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 24 Weeks - 34 Weeks

Code: NCT06612541·Recruiting

Apply to this trial

Evaluation of Eye Gaze Sharing in the Operating Room

for Kidney Stones

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07173309·Recruiting

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Evaluating the Effectiveness of a Multi-level Health-Related Social Needs Initiative

for Type 2 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06831162·Enrolling By Invitation

Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy

for Schizophrenia Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT06835556·Recruiting

Apply to this trial

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

for Delirium

14 locations incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06192615·Phase 3·Recruiting

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The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life

for Systemic Sclerosis (SSc)

4 locations incl. New Orleans

Sponsor: Robyn T. Domsic, MD, MPH

Sex: All·Age: 18+

Code: NCT06675344·Recruiting

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A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage

for Post Partum Hemorrhage

1 location in Nashville

Sponsor: Holly Ende

Sex: Female·Age: All ages

Code: NCT06513351·Recruiting

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

88 locations incl. Alexander City

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting

Apply to this trial

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for Parenteral Nutrition Associated Liver Disease (PNALD)

10 locations incl. Fountain Valley

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Day - 17

Code: NCT06274788·Recruiting

Apply to this trial

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

13 locations incl. Tucson

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting

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A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for Colorectal Neoplasms

Drug: Amivantamab

70 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06750094·Phase 3·Recruiting

Apply to this trial

Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty

for Osteoarthritis, Knee

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 50+

Code: NCT06083480·Phase 4·Recruiting

Apply to this trial

Mobile Health Intervention to Improve Exercise in Pediatric PH

for Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 10 - 21

Code: NCT06549452·Recruiting

Apply to this trial

CoMind Early Feasibility Study

for Intracranial Pressure

14 locations incl. Sacramento

Sponsor: CoMind Technologies Limited

Sex: All·Age: 18+

Code: NCT06368648·Recruiting

Apply to this trial

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

29 locations incl. Anaheim

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting

Apply to this trial