Paid Clinical Trials in Minnesota

Minnesota has 2,377 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,375 clinical trials

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SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

43 locations incl. Jonesboro

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting

Apply to this trial

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

237 locations incl. Little Rock

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 60+

Code: NCT05976763·Phase 3·Recruiting

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An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for Chronic Kidney Disease (CKD)

9 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT05106387·Recruiting

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Feasibility of Transcranial Focused Ultrasound to Measure Brain Tumor

for Cranial Neurosurgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05755399·Recruiting

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

60 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

22 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting

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Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors

for Estrogen Receptor-Positive Breast Carcinoma

23 locations incl. Albert Lea

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06028022·Phase 2·Recruiting

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SAfety of Regional Citrate Anticoagulation (SARCA Study)

for Acute Kidney Injury

10 locations incl. Little Rock

Sponsor: Fresenius Medical Care North America

Sex: All·Age: 18+

Code: NCT05339139·Phase 3·Recruiting

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A Study of Invasive Hemodynamic for MACHD Registry

for Healthy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05849025·Recruiting

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Using Facebook to Support Opioid Recovery Among American Indian Women

for Opioid Use Disorder

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05995886·Recruiting

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Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

for Barrett Esophagus

5 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 90

Code: NCT06071845·Recruiting

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DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

for Small Cell Lung Carcinoma

16 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT05882058·Phase 2·Recruiting

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Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

for Hodgkin Lymphoma

428 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06002828·Recruiting

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Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for Plasma Cell Myeloma

397 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: All ages

Code: NCT05561387·Phase 3·Recruiting

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INTERogating Cancer for Etiology, Prevention and Therapy Navigation

for Cancer

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06008392·Recruiting

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ETHAN - ET for Male BC

for Male Breast Cancer

8 locations incl. Washington D.C.

Sponsor: Jose Pablo Leone

Sex: Male·Age: 18+

Code: NCT05501704·Phase 2·Recruiting

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A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

for Alopecia Areata

Drug: Upadacitinib

77 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12 - 63

Code: NCT06012240·Phase 3·Recruiting

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MR Elastography of Cognitive Impairment

for Alzheimer Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06029114·Enrolling By Invitation

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

for Metastatic Colorectal Adenocarcinoma

184 locations incl. Kingman

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05673148·Phase 3·Recruiting

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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

148 locations incl. Dothan

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05952557·Phase 3·Recruiting

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

178 locations incl. Alexander City

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting

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The Use of Ultrasound in Assessing Post-prostatectomy Erectile Dysfunction

for Prostate Adenocarcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Male·Age: 40+

Code: NCT05109208·Recruiting

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

22 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting

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Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

for Diffuse Glioma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05717153·EARLY_Phase 1·Recruiting

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The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

for Spinal Cord Injuries

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT05741788·Recruiting

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Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

for Hidradenitis Suppurativa

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06058520·EARLY_Phase 1·Recruiting

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Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

for Obesity

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75

Code: NCT06226077·Phase 1, Phase 2·Recruiting

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Beetroot Juice and Sleep

for Healthy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05864521·Recruiting

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Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

for Fallopian Tube Carcinosarcoma

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05920798·Phase 1, Phase 2·Recruiting

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Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for Neuroendocrine Tumors Unresectable

19 locations incl. Jacksonville

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05636618·Phase 1, Phase 2·Recruiting

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

104 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting

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Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

10 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05673200·Phase 1·Recruiting

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Exercise Response in Humans With Obesity

for Obese

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 20 - 45

Code: NCT05857150·Recruiting

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Voice Analysis Technology to Detect and Manage Depression and Anxiety in Cardiac Rehabilitation

for Myocardial Infarction

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05371470·Enrolling By Invitation

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

for Obesity

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 22 - 69

Code: NCT05739162·Recruiting

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Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

for Lumbar Spinal Stenosis

6 locations incl. Beverly Hills

Sponsor: Columbia University

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06034405·Recruiting

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Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

for Hearing

2 locations incl. Minneapolis

Sponsor: Marquette University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06465979·Recruiting

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Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

for Opioid-Induced Esophageal Dysfunction

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05854303·Recruiting

Apply to this trial

CTSN Embolic Protection Trial

for Delirium

24 locations incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting

Apply to this trial