Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)

for Cannabis Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 15 - 18·Accepts healthy volunteers

Code: NCT06124846·Recruiting

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A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)

for Coarctation of Aorta

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06150560·Phase 3·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion

for Immunoglobulin Light Chain (AL) Amyloidosis

Drug: Etentamig

12 locations incl. Miami

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06158854·Phase 1, Phase 2·Recruiting

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Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

44 locations incl. Homewood

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

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Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

for Open GI Surgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06300892·Recruiting

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Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy

for Neck Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 39

Code: NCT06312696·Recruiting

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Ketamine Treatment for PTSD and MDD in TBI

for PTSD, Post Traumatic Stress Disorder

1 location in Minneapolis

Sponsor: Minneapolis Veterans Affairs Medical Center

Sex: All·Age: 18 - 75

Code: NCT06228391·Phase 2·Not Yet Recruiting

Open Label, Controlled, Post Marketing, Registry Study of Ribociclib (Ribo) Treatment Adherence and Patient Reported Outcomes in Participants Using ReX Technology Platform

for Any Solid Oral Medication

Drug: Ribociclib

4 locations incl. Minneapolis

Sponsor: Dosentrx Ltd.

Sex: All·Age: 18+

Code: NCT06344416·Recruiting

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Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy

46 locations incl. Alabaster

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06291376·Phase 3·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

104 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

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A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

for Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV)

16 locations incl. Beverly Hills

Sponsor: Fate Therapeutics

Sex: All·Age: 12 - 70

Code: NCT06308978·Phase 1·Recruiting

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Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

for Endometrial Carcinoma

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: Female·Age: 55+

Code: NCT06365905·Recruiting

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Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

for Arrhythmogenic Right Ventricular Cardiomyopathy

7 locations incl. San Francisco

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 65

Code: NCT06228924·Phase 1·Recruiting

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Use of New Generation Fetoscopes in Pregnancies Affected by Fetal Diseases Amenable to Fetoscopy Therapy

for In Utero Procedure Affecting Fetus or Newborn

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06281730·Enrolling By Invitation

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

for Gastric Antral Vascular Ectasia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 19+

Code: NCT06306963·Recruiting

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Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

7 locations incl. Birmingham

Sponsor: Molecure S.A.

Sex: All·Age: 18+

Code: NCT06205121·Phase 2·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

for Solid Tumor

4 locations incl. Phoenix

Sponsor: SparX Biotech(Jiangsu) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06259552·Phase 1·Recruiting

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Aim 3 Particle Swarm Optimization PIGD

for Parkinson's Disease and Parkinsonism

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT05934747·Recruiting

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

38 locations incl. Phoenix

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting

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ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

for Aortic Valve Stenosis

67 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05932615·Enrolling By Invitation

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

for Diffuse Midline Glioma, H3 K27M-Mutant

1 location in Minneapolis

Sponsor: OX2 Therapeutics

Sex: All·Age: 2 - 25

Code: NCT06305910·Phase 1·Recruiting

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An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for Systemic Lupus Erythematosus

22 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 5 - 17

Code: NCT05835310·Phase 3·Recruiting

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Mitigating PTSD-CUD After Sexual Assault

for Posttraumatic Stress Disorder

6 locations incl. Minneapolis

Sponsor: University of Nevada, Las Vegas

Sex: Female·Age: 18+

Code: NCT05989841·Phase 1, Phase 2·Recruiting

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

61 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting

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Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma

for Bone Sarcoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06409013·Recruiting

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A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

141 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

41 locations incl. Fayetteville

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting

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Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

for Myocardial Infarction

2 locations incl. Rochester

Sponsor: AliveCor

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06271577·Recruiting

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Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks

for Ankle Block

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05425979·Phase 4·Enrolling By Invitation

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

59 locations incl. Duarte

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting

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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

37 locations incl. Huntsville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting

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First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Advanced Metastatic Castration-resistant Prostate Cancer

4 locations incl. Duarte

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06217822·Phase 1·Recruiting

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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

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Udall Project 1 Aim 4

for Parkinsons Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05568199·Recruiting

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Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

for Liver Transplant

18 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06075745·Phase 2·Recruiting

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The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

for Death

21 locations incl. Anchorage

Sponsor: Mayo Clinic

Sex: All·Age: 0 Days+

Code: NCT06087224·Recruiting

Apply to this trial

A Study of Mayo Clinic CV Research Heart & Voice Study

for Cardiovascular Diseases

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07224685·Recruiting

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MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06042725·Phase 1·Recruiting

Apply to this trial