Breast oncology Clinical Trials in Miami, FL
As of June 2026, 46 paid clinical trials are recruiting for Breast oncology in Miami, Florida. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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46 clinical trials for Breast oncology
·Clear filters·↓ Download CSVSignatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Breast Re-irradiation After Second Ipsilateral Lumpectomy
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Precise Oncology Interventions in Nutrition and Training (OnPoint)
Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
ATEMPT 2.0: Adjuvant T-DM1 vs TH
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
SABER Study for Selected Early Stage Breast Cancer
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
About research studies in Miami
Miami has approximately 1,413 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Miami
Researchers run research studies in Miami, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Miami | Multiple Myeloma, Amyotrophic Lateral Sclerosis, Cancer | 261 |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm, Stage IV Lung Cancer AJCC v8 | 85 |
| Nicklaus Children's Hospital | Neuroblastoma, Malignant Solid Neoplasm, Osteosarcoma | 60 |
| Miami Cancer Institute | Acute Myeloid Leukemia, Breast Cancer, Brain Cancer | 51 |
| UM Sylvester Comprehensive Cancer Center at Kendall | Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Melanoma, Stage IV Lung Cancer AJCC v8 | 36 |
| Sylvester Comprehensive Cancer Center | Multiple Myeloma, Breast Cancer, Chronic Lymphocytic Leukemia | 29 |
| University of Miami Miller School of Medicine | Alopecia, Amyotrophic Lateral Sclerosis, Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | 19 |
| Miami Cancer Institute at Baptist Health, Inc. | Breast Cancer, Cancer, Brain Metastases | 18 |
| University of Miami Hospital | Dystonia, Essential Tremor, Parkinson Disease | 18 |
| GSK Investigational Site | HIV Infections, Chickenpox, Gastrointestinal Neoplasms | 17 |
| Bascom Palmer Eye Institute | Stargardt Disease, Eye Diseases, Glaucoma | 17 |
| New Horizon Research Center | Obesity, Overweight, Chronic Pain | 14 |
| Jackson Memorial Hospital | Intracerebral Hemorrhage, Ischemic Stroke, Traumatic Brain Injury | 13 |
| Florida International University | Electronic Cigarette Use, Hiv, Anxiety Symptoms | 12 |
| University of Miami Hospital and Clinics | Multiple Myeloma, Advanced Colorectal Cancer (Part 1), Breast Cancer | 12 |
| Baptist Health South Florida | Heart Failure, Aneurysmal Subarachnoid Hemorrhage (aSAH), Breast Cancer | 10 |
| University of Miami Health System | Aneurysm, Brain, Artificial Intelligence (AI), Blood Vessel Injury | 10 |
| Baptist Hospital of Miami | Heart Valve Diseases, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 9 |
| Clinical Pharmacology of Miami | Healthy, Obesity, Type 2 Diabetes | 9 |
| University of Miami Sylvester Comprehensive Cancer Center | Advanced Solid Tumors, Abdominal Neoplasm, Acute Myeloid Leukemia | 9 |
| Visionary Investigators Network | AChR-Ab Seropositive Generalized Myasthenia Gravis, Generalized Myasthenia Gravis, Generalized Myasthenia Gravis (gMG) | 9 |
| Miami VA Healthcare System, Miami, FL | Epilepsy, Atherosclerosis, Carcinoma, Hepatocellular | 8 |
| University of Miami - Sylvester Comprehensive Cancer Center | Breast Cancer, Advanced Solid Tumor, Lung Cancer | 8 |
| University of Miami Hospital and Clinics, Sylvester Cancer Center | Neoplasm Metastasis, Breast Cancer, Breast Neoplasms | 8 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia, Tardive Dyskinesia | 7 |
Active & Upcoming Studies in Miami (2026)
Recruiting trials in Miami grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (395 active studies)
- Intralesional Chemotherapy (IC): Cisplatin + Epinephrine · Phase 2 · University of Miami
- Study Evaluating Safety, Tolerability, and Metabolism of Niraparib · Phase 4 · University of Miami
Neurology & pain (100 active studies)
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain · Phase 2 · Eli Lilly and Company
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain · Phase 2 · Eli Lilly and Company
Diabetes & metabolic (72 active studies)
- PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon) · Phase 4 · University of Miami
- PLAY2CONTROL Study · University of Miami
Cardiovascular (50 active studies)
- The Pharmacokinetics and Pharmacodynamics Study of CG-0255 Besylate and Plavix® in Healthy Participants · Phase 1 · Shanghai CureGene Pharmaceutical Co., Ltd.
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Mental health & behavior (49 active studies)
- The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · Duke University
- Implementing Depression and Adherence Treatment · University of Miami
HIV / STI (33 active studies)
- Implementing Depression and Adherence Treatment · University of Miami
- PrEP & Soccer: A Program for Pharmacy Chains to Increase PrEP Awareness and Access Among Men · University of Miami
Pediatric (12 active studies)
- AIR Support: Artificially Intelligent Robot (AIR) Support for Pediatric Asthma Education · University of Miami
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Vaccines (10 active studies)
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
Eye & vision (8 active studies)
- Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye · Phase 2 · University of Miami
- Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use · Phase 4 · University of Miami
Common conditions studied in Miami
- Breast Cancer (33 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (23 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Prostate Cancer (20 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Alzheimer Disease (17 active studies). Alzheimer's research investigates anti-amyloid antibodies, tau-targeted therapies, and lifestyle interventions aimed at slowing cognitive decline.
- Multiple Myeloma (17 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ulcerative Colitis (17 active studies). Ulcerative colitis trials examine biologic therapies, S1P receptor modulators, and oral small molecules for steroid-sparing remission.
Leading research sponsors in Miami
- University of Miami
- Eli Lilly and Company
- National Cancer Institute (NCI)
- AstraZeneca
- Pfizer
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Miami. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Miami
Hipa.ai aggregates every recruiting study in Miami from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Miami?
There are approximately 1,413 recruiting clinical trials in Miami, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Miami pay participants?
Most recruiting trials in Miami compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Miami?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Miami?
The most common conditions under active study in Miami include Breast Cancer (33), Obesity (23), Prostate Cancer (20), Alzheimer Disease (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Miami?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Miami on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Miami?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Miami?
Recruiting research sites in Miami include University of Miami, University of Miami Miller School of Medicine-Sylvester Cancer Center, Nicklaus Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Miami right now?
The largest active categories in Miami are Cancer & tumors (395), Neurology & pain (100), Diabetes & metabolic (72). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.