Paid Clinical Trials in Maryland

Maryland has 2,900 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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2,900 clinical trials

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Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)

for Mild Cognitive Impairment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 60 - 95·Accepts healthy volunteers

Code: NCT04765137·Phase 2·Recruiting

Apply to this trial

ROSE for Improved Molecular Marker Testing Via EBUS

for Non-small Cell Lung Cancer (NSCLC)

4 locations incl. Chicago

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT04945317·Enrolling By Invitation

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

for Thyroid Eye Disease

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06275373·Recruiting

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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

28 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

for Locally Advanced (Inoperable) or Metastatic Breast Cancer

54 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT04862663·Phase 3·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

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Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery

for Intrahepatic Cholangiocarcinoma

10 locations incl. Bethesda

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04891289·Phase 2·Recruiting

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Global PNH Patient Registry

for Paroxysmal Nocturnal Hemoglobinuria

1 location in Bethesda

Sponsor: Aplastic Anemia and MDS International Foundation

Sex: All·Age: All ages

Code: NCT05755867·Recruiting

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A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

for Chronic Lymphocytic Leukemia (CLL)

16 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT04830137·Phase 1·Recruiting

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PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

for Prostate Cancer

3 locations incl. Baltimore

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 18+

Code: NCT04995198·Recruiting

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A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

for Ventilator Associated Pneumonia

8 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT04987840·Enrolling By Invitation

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

for Androgen Insensitivity Syndrome

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 - 99·Accepts healthy volunteers

Code: NCT04708431·Recruiting

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Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome

for Cushing Syndrome

5 locations incl. San Francisco

Sponsor: RECORDATI GROUP

Sex: All·Age: 2 - 17

Code: NCT03708900·Phase 2·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for Depression

Drug: Cariprazine

69 locations incl. Bentonville

Sponsor: AbbVie

Sex: All·Age: 10 - 17

Code: NCT04777357·Phase 3·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

for Anatomic Stage III Breast Cancer AJCC v8

4 locations incl. Gainesville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04550494·Phase 2·Recruiting

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ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

for Acute Hepatic Porphyria

13 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 12+

Code: NCT04883905·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

14 locations incl. San Francisco

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting

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Data Collection Study of Pediatric and Adolescent Gynecology Conditions

for Disorders of Sex Development (DSD)

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT04717349·Recruiting

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Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer

Drug: Durvalumab

5 locations incl. Chicago

Sponsor: Muhammad Furqan

Sex: All·Age: 18+

Code: NCT04699838·Phase 2·Recruiting

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Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

12 locations incl. Phoenix

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting

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Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

for Castration-Resistant Prostate Carcinoma

4 locations incl. Baltimore

Sponsor: University of Washington

Sex: Male·Age: 18+

Code: NCT04489719·Recruiting

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Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for Propionic Acidemia

15 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: All ages

Code: NCT04159103·Phase 1, Phase 2·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Handoffs and Transitions in Critical Care - Understanding Scalability

for Patient Handoff

5 locations incl. Baltimore

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04571749·Enrolling By Invitation

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

for Advanced or Metastatic Solid Tumor

8 locations incl. Long Beach

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT04617522·Phase 1·Recruiting

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CORE-COMPARE Pilot Study

for Coronary Heart Disease (CHD)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 85

Code: NCT06170541·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

for Familial Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 30 - 120·Accepts healthy volunteers

Code: NCT04431024·Recruiting

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A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

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Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

for Traumatic Brain Injury

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 79

Code: NCT05084352·Recruiting

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Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

for Depressive Symptoms

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 85

Code: NCT04123314·EARLY_Phase 1·Recruiting

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ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

for Transitional Cell Cancer of Renal Pelvis and Ureter

12 locations incl. Irvine

Sponsor: Steba Biotech S.A.

Sex: All·Age: 18+

Code: NCT04620239·Phase 3·Recruiting

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REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

for Lumbar Spinal Stenosis

10 locations incl. Santa Rosa

Sponsor: Pacific Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05504499·Recruiting

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Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer

for Recurrent Thyroid Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 85

Code: NCT04892303·Phase 1·Recruiting

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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for Locally Advanced or Metastatic Non-Small Cell Lung Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT04686305·Phase 1·Recruiting

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Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

for Advanced Solid Tumor Cancer

Drug: ABBV-CLS-484

15 locations incl. Tucson

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18+

Code: NCT04777994·Phase 1·Recruiting

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The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population

for Hypogonadism

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06247267·Recruiting

Apply to this trial