Paid Clinical Trials in Maryland

Maryland has 2,891 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,891 clinical trials

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A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

for Bipolar Disorder Type I With Mania

Drug: KarXT

52 locations incl. Glendale

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT06929273·Phase 3·Recruiting

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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

18 locations incl. Arcadia

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting

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DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

for Solid Tumors

15 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06953089·Phase 2·Recruiting

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Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency

for Premature Ovarian Insufficiency

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: Female·Age: 11 - 19·Accepts healthy volunteers

Code: NCT06851754·Phase 3·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

56 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting

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Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study

for CD40L-HyperIgM Syndrome

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: Male·Age: 37 - 120

Code: NCT06959771·Phase 1, Phase 2·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for Colon Adenocarcinoma

Drug: Calderasib

26 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06997497·Phase 3·Recruiting

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Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Eye Pressure in Non-Caucasian Patients With Open Angle Glaucoma

for Primary Open Angle Glaucoma (POAG)

1 location in Elkridge

Sponsor: Select Eye Care

Sex: All·Age: 18+

Code: NCT07147647·Recruiting

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Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2

for PASC Post Acute Sequelae of COVID 19

1 location in Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07278388·Recruiting

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Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

for Acute Ischemic Stroke

3 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT06440707·Phase 2·Recruiting

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TANDem-2: Closing the Gap to Interventions for TAND

for Adult Caregivers of Individuals With TSC

1 location in Silver Spring

Sponsor: Vrije Universiteit Brussel

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06879665·Enrolling By Invitation

A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

for Chronic Hepatitis B Infection

18 locations incl. Chandler

Sponsor: Aligos Therapeutics

Sex: All·Age: 18 - 65

Code: NCT06963710·Phase 2·Recruiting

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A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

for HER2-negative Breast Cancer Patients With Brain Metastases

17 locations incl. Duarte

Sponsor: Biostar Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06764940·Phase 2·Recruiting

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

59 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

60 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting

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A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

for Chronic Spontaneous Urticaria (CSU)

Drug: Remibrutinib

128 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06868212·Phase 3·Recruiting

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Prospective Study to Assess a Diagnostic Aid for Cancer

for Cancer

39 locations incl. Coronado

Sponsor: Harbinger Health

Sex: All·Age: 45+

Code: NCT07046260·Recruiting

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

31 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

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NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

for Schizophrenia

Drug: NBI-1117568

49 locations incl. Bryant

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07114874·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

for Alzheimer Disease

Drug: KarXT

40 locations incl. Scottsdale

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011732·Phase 3·Recruiting

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A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

for Developmental and Epileptic Encephalopathy 1

6 locations incl. La Jolla

Sponsor: Praxis Precision Medicines

Sex: All·Age: 2 - 65

Code: NCT07010471·Phase 3·Recruiting

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Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

for Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06885697·Phase 1·Recruiting

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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for Major Depressive Disorder

35 locations incl. Dothan

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07076407·Phase 3·Recruiting

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Photobiomodulation and Tooth Analgesia

for Dental Anaesthesia

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 6 - 12·Accepts healthy volunteers

Code: NCT06691269·Recruiting

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An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-sensitive Prostate Cancer

Drug: JSB462

21 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT06991556·Phase 2·Recruiting

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Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth

for Amyotrophic Lateral Sclerosis

1 location in Salisbury

Sponsor: TidalHealth, Inc.

Sex: All·Age: 18+

Code: NCT07491484·Recruiting

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Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

for Posttraumatic Headache

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06608277·Phase 2·Recruiting

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

13 locations incl. Phoenix

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting

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TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

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Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers

for Metastatic Malignant Solid Neoplasm

Drug: Pidnarulex

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06606990·Phase 1·Recruiting

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Study to Evaluate the Safety, Tolerability, and Efficacy of PEP-TISSEEL in Subjects With Chronic Radiation Ulcer

for Chronic Radiation Ulcer

1 location in Bethesda

Sponsor: Rion Inc.

Sex: All·Age: 18+

Code: NCT06793748·Phase 1, Phase 2·Not Yet Recruiting

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for Breast Neoplasms

53 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06966700·Phase 3·Recruiting

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Safety, and Efficacy Study of ShigETEC, a Live, Attenuated, Oral Combination Vaccine to Prevent Shigella and ETEC Disease Delivered to Healthy Adults Ages 18 to 50 Years Old

for Shigella

1 location in Baltimore

Sponsor: Eveliqure Biotechnologies GmbH

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07049159·Phase 2·Recruiting

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PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)

for Hematologic Malignancies

11 locations incl. Duarte

Sponsor: Pulmotect, Inc.

Sex: All·Age: 18+

Code: NCT06665100·Phase 2·Recruiting

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E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

Apply to this trial