Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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3,602 clinical trials

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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

for Anarthria

2 locations incl. Stanford

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT05724173·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

for Adenocarcinoma, Pancreatic Ductal

Drug: Atezolizumab

32 locations incl. Los Angeles

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT05968326·Phase 2·Recruiting

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

22 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting

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A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

8 locations incl. Palo Alto

Sponsor: Bristol-Myers Squibb

Sex: Male·Age: 18+

Code: NCT06067841·Phase 1·Recruiting

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PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

for Malignant Female Reproductive System Neoplasm

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18+

Code: NCT06089083·Recruiting

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A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

for Metastatic Breast Cancer

12 locations incl. Birmingham

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06099769·Phase 2·Recruiting

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SAfety of Regional Citrate Anticoagulation (SARCA Study)

for Acute Kidney Injury

10 locations incl. Little Rock

Sponsor: Fresenius Medical Care North America

Sex: All·Age: 18+

Code: NCT05339139·Phase 3·Recruiting

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The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

for Aortoiliac Occlusive Disease

26 locations incl. Little Rock

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05811364·Recruiting

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Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

for Stress

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 12 - 25·Accepts healthy volunteers

Code: NCT06038318·Recruiting

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A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

for Multiple Myeloma

Drug: Daratumumab

11 locations incl. Boston

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06083922·Phase 2·Recruiting

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PRIMARY Ancillary Substudy

for Mitral Valve Prolapse

16 locations incl. Los Angeles

Sponsor: Annetine Gelijns

Sex: All·Age: 60+

Code: NCT07103733·Recruiting

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DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

for Small Cell Lung Carcinoma

16 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT05882058·Phase 2·Recruiting

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Clinical Trial of Blenderized Tube Feeds Varying in Viscosity

for Feeding Disorders

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1+

Code: NCT05417958·Recruiting

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ETHAN - ET for Male BC

for Male Breast Cancer

8 locations incl. Washington D.C.

Sponsor: Jose Pablo Leone

Sex: Male·Age: 18+

Code: NCT05501704·Phase 2·Recruiting

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Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

6 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting

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A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

for Alopecia Areata

Drug: Upadacitinib

77 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12 - 63

Code: NCT06012240·Phase 3·Recruiting

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Optimizing and Advancing SBIRT in Schools

for Adolescent Drinking

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14 - 19

Code: NCT06206161·Enrolling By Invitation

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

32 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting

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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

for Metastatic Colorectal Adenocarcinoma

184 locations incl. Kingman

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05673148·Phase 3·Recruiting

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The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

for Peripheral Arterial Disease

10 locations incl. Salinas

Sponsor: Endologix

Sex: All·Age: All ages

Code: NCT06315023·Enrolling By Invitation

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

for Advanced Solid Tumors

7 locations incl. Los Angeles

Sponsor: LigaChem Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05941507·Phase 1, Phase 2·Recruiting

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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

148 locations incl. Dothan

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05952557·Phase 3·Recruiting

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

22 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting

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The Arch Watch Study: An Integrated Evaluation of Hemodynamics in Infants With Suspected Coarctation of the Aorta

for Coarctation of the Aorta

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Days - 60 Days·Accepts healthy volunteers

Code: NCT05880576·Enrolling By Invitation

Supplemental Oxygen in Pulmonary Embolism (SO-PE)

for Pulmonary Embolism

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05891886·EARLY_Phase 1·Recruiting

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AWARE: Management of ADHD in Autism Spectrum Disorder

for ADHD

10 locations incl. Irvine

Sponsor: Daniel Coury

Sex: All·Age: 4 - 17

Code: NCT05916339·Phase 4·Recruiting

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Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

for Acute Suicidal Depression (ASD)

9 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 90

Code: NCT06034821·Phase 4·Enrolling By Invitation

Impact of Intensive Computerized Cognitive Training

for Acquired Brain Injury

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 25 - 65

Code: NCT06130735·Recruiting

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International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

for Intracranial Aneurysm

10 locations incl. Coral Gables

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT06174727·Recruiting

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Increasing Access to Definitive Treatment for Prostate Cancer

for Prostate Cancer

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 22+

Code: NCT06034431·Not Yet Recruiting

Patient-centered, Optimal Integration of Survivorship and Palliative Care

for Stage IV Non-small Cell Lung Cancer

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04900935·Recruiting

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Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

for Corneal Ulcer

4 locations incl. Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05705024·Phase 2·Recruiting

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A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies

for GIST

11 locations incl. Los Angeles

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT05957367·Phase 1, Phase 2·Recruiting

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Implementation of a Consensus-Based Discharge Protocol for Preterm Infants With Lung Disease

for Bronchopulmonary Dysplasia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Days - 1

Code: NCT05285345·Recruiting

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A Long-term Follow-up Study of Participants Who Received Delandistrogene Moxeparvovec (SRP-9001) in a Previous Clinical Study

for Duchenne Muscular Dystrophy

22 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT05967351·Phase 3·Enrolling By Invitation

Cryoablation+Ipilimumab+Nivolumab in Melanoma

for Metastatic Melanoma

Drug: Ipilimumab

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05779423·Phase 2·Recruiting

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Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

for Heart Failure

7 locations incl. Palm Springs

Sponsor: Analog Device, Inc.

Sex: All·Age: 18+

Code: NCT05650541·Recruiting

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Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

for Obesity

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18 - 70

Code: NCT05711758·Recruiting

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An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

for Rectal Cancer

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05914766·Recruiting

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