Paid Clinical Trials in Massachusetts

Massachusetts has 3,584 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,584 clinical trials

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Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

for Major Depressive Disorder

2 locations incl. Sunnyvale

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT06376734·Phase 2·Recruiting

Apply to this trial

Pilot of an Online Sexual Health Program

for Program, Communication

1 location in Wellesley

Sponsor: Wellesley College

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT06564025·Recruiting

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A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

for Chronic Lymphocytic Leukaemia

13 locations incl. Boston

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06564038·Phase 1, Phase 2·Recruiting

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Family Connections

for Emotional Disturbance

1 location in Cambridge

Sponsor: Cambridge Health Alliance

Sex: All·Age: 3 - 18

Code: NCT06662357·Recruiting

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

53 locations incl. Birmingham

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting

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An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for Recurrent Pericarditis

17 locations incl. Tucson

Sponsor: Zomagen Biosciences Ltd.

Sex: All·Age: 18 - 75

Code: NCT06836232·Phase 2·Recruiting

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A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

for Sexual Dysfunction

3 locations incl. Coral Gables

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06541002·Recruiting

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Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

for Sarcoma

3 locations incl. Boston

Sponsor: David S Shulman, MD

Sex: All·Age: 12 - 49

Code: NCT06709495·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

80 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting

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Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

for Advanced or Metastatic Solid Tumors

5 locations incl. Boston

Sponsor: Innate Pharma

Sex: All·Age: 18+

Code: NCT06781983·Phase 1·Recruiting

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Diabetes Body Project 2

for Eating Disorders

1 location in Boston

Sponsor: Joslin Diabetes Center

Sex: Female·Age: 18 - 40

Code: NCT07468188·Recruiting

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Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

for Depressive Disorder, Major

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 25 - 50

Code: NCT06136546·Phase 2·Recruiting

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A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

6 locations incl. Tampa

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06697184·Phase 1, Phase 2·Recruiting

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Mindfulness for Cognition in Early-stage Alzheimer's Disease

for Mild Cognitive Impairment (MCI)

1 location in Boston

Sponsor: VA Boston Healthcare System

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06792877·Recruiting

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Dance Study for Post-surgical Pain in Breast Cancer Survivors

for Breast Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06758102·Recruiting

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Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

18 locations incl. Little Rock

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06786624·Phase 3·Recruiting

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Advanced Imaging for Pulmonary Fibrosis

for Pulmonary Fibrosis

1 location in Boston

Sponsor: Peter Caravan

Sex: All·Age: 18 - 80

Code: NCT06532071·Phase 2·Recruiting

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Epco, Zanu, Ritux for R/R FL or MZL

for Follicular Lymphoma

3 locations incl. Boston

Sponsor: Reid Merryman, MD

Sex: All·Age: 18+

Code: NCT06563596·Phase 2·Recruiting

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A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for Chronic Graft-versus-host-disease

33 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06585774·Phase 3·Recruiting

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Transcranial Stimulation Combined With Auditory Training

for Difficulties Understanding Speech in Noise

1 location in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 50+

Code: NCT06738030·Not Yet Recruiting

Synergy Between Patient and Clinician: Using a Trauma-Informed Care Plan

for Trauma and Stressor Related Disorders

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06330753·Enrolling By Invitation

Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer

for Ovarian Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT06543537·Recruiting

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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Embolization Treatment of Chronic Refractory Shoulder Tendinopathy

for Shoulder Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21 - 80

Code: NCT06095050·Recruiting

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A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

for Muscular Atrophy, Spinal

10 locations incl. Orange

Sponsor: Biogen

Sex: All·Age: 3+

Code: NCT06555419·Phase 1·Recruiting

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Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

for Stress Disorders, Post-Traumatic

1 location in Boston

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT06088303·Recruiting

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Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

for Insomnia

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65+

Code: NCT06375265·Recruiting

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Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

for Rhegmatogenous Retinal Detachment

1 location in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06033703·Phase 1, Phase 2·Recruiting

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A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula

for End Stage Renal Disease

7 locations incl. Long Beach

Sponsor: Laminate Medical Technologies

Sex: All·Age: 18 - 80

Code: NCT06516653·Recruiting

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Post-Market Clinical Investigation Plan- Collagen Dural Regeneration Matrix (DuraMatrix-Onlay Plus)

for Repair of Dura Mater

2 locations incl. Augusta

Sponsor: Collagen Matrix

Sex: All·Age: 18+

Code: NCT06802133·Recruiting

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Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

for Chronic Pain

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50+

Code: NCT06246929·Recruiting

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BMT-CARE: Psychosocial Intervention for Transplant Caregivers

for Bone Marrow Transplant Complications

3 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06472089·Recruiting

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An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. Los Angeles

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06589596·Phase 1·Recruiting

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A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

for Sickle Cell Disease

Drug: Etavopivat

39 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 2+

Code: NCT06609226·Phase 3·Recruiting

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A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

60 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

23 locations incl. Phoenix

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

23 locations incl. Glendale

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06807424·Phase 3·Recruiting

Apply to this trial