Paid Clinical Trials in Massachusetts

Massachusetts has 3,587 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,584 clinical trials

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A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

for Triple Negative Breast Cancer

6 locations incl. Duarte

Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd.

Sex: All·Age: 18+

Code: NCT06908928·Phase 1·Recruiting

Apply to this trial

The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults

for Aging

2 locations incl. Boston

Sponsor: Mayo Clinic

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06940037·Recruiting

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for Prurigo Nodularis

Drug: Nemolizumab

39 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT06988618·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors

for Stroke

1 location in Boston

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 85

Code: NCT06797154·Recruiting

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A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

for Primary Hyperaldosteronism

Drug: Baxdrostat

21 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07007793·Phase 3·Recruiting

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Building Connections

for Cancer Colorectal

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 75

Code: NCT07091032·Recruiting

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Optical Coherence Tomography (OCT) Based Intraoral Scanner

for The Focus of the Study is to Evaluate the Efficacy of OCT in Scanning and Reconstructing General Tooth and Gum Anatomy

1 location in Somerville

Sponsor: Perceptive Technologies, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07092592·Not Yet Recruiting

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

for Alzheimer's Disease

24 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT07094516·Phase 2·Recruiting

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A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

for Melanoma (Skin Cancer)

9 locations incl. Newport Beach

Sponsor: Linnaeus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06624644·Phase 2, Phase 3·Recruiting

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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting

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Axatilimab for Sclerotic Chronic Graft-versus-Host Disease

for Chronic Graft Versus Host Disease

3 locations incl. Tampa

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07011810·Phase 2·Recruiting

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A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for Breast Neoplasms

16 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07114601·Phase 1·Recruiting

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Discontinuation of Anticoagulations After Successful Catheter Ablation of Atrial Fibrillation

for Atrial Fibrillation (AF)

1 location in Boston

Sponsor: China National Center for Cardiovascular Diseases

Sex: All·Age: 18+

Code: NCT06615596·EARLY_Phase 1·Recruiting

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Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

for X-Linked Chronic Granulomatous Disease

8 locations incl. Los Angeles

Sponsor: Ensoma

Sex: Male·Age: 3 Months+

Code: NCT06876363·Phase 1, Phase 2·Recruiting

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Accelerated TMS for Perinatal Depression

for Perinatal Depression

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 55

Code: NCT06968390·Recruiting

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

27 locations incl. Huntington Beach

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting

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Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

for Post Traumatic Stress Disorder

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07079761·Phase 2·Recruiting

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A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

for Tophaceous Gout

Drug: Dotinurad

86 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089888·Phase 3·Recruiting

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Understanding Vape Marketing Study

for E-cigarette

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07129265·Enrolling By Invitation

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting

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Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

for Heart Surgery

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 17

Code: NCT06721455·Recruiting

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Study Evaluating the Efficacy and Safety of Artesunate

for CMV Infection

2 locations incl. Boston

Sponsor: Amivas Inc.

Sex: All·Age: 18+

Code: NCT06853184·Phase 2·Recruiting

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A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

for Advanced Solid Tumor

15 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06997029·Phase 1·Recruiting

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Gamified Learning for Pressure Injury Prevention

for Pressure Injuries

1 location in Boston

Sponsor: Mehmet Akif Ersoy University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07028892·Not Yet Recruiting

Individualizing Treatment for Asthma in Primary Care (Full Study)

for Asthma

13 locations incl. Aurora

Sponsor: DARTNet Institute

Sex: All·Age: 13 - 75

Code: NCT07052942·Phase 4·Recruiting

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A Study of Dotinurad Versus Allopurinol in Participants With Gout

for Gout

Drug: Dotinurad

80 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089875·Phase 3·Recruiting

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Minocycline Plus Amiodarone Versus Amiodarone Alone for the Prevention of Atrial Fibrillation After Cardiac Surgery

for Atrial Fibrillation

1 location in Melrose

Sponsor: Baystate Medical Center

Sex: All·Age: 18+

Code: NCT01422148·Phase 2·Not Yet Recruiting

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for KRAS Altered Advanced or Metastatic Solid Tumors

10 locations incl. Duarte

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07094113·Phase 1·Recruiting

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CUE-102 in Recurrent Glioblastoma

for Recurrent Glioblastoma

2 locations incl. Boston

Sponsor: David Reardon, MD

Sex: All·Age: 18+

Code: NCT06917885·Phase 1·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting

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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

for Adjustment Disorder

30 locations incl. Birmingham

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 80

Code: NCT07002034·Phase 2·Recruiting

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Additively Versus Subtractively Manufactured Implant Supported Fixed Dental Prostheses

for Dental Prosthesis, Implant-Supported

1 location in Boston

Sponsor: Harvard Medical School (HMS and HSDM)

Sex: All·Age: 20+

Code: NCT07090863·Not Yet Recruiting

Atrial Fibrillation Risk Estimation With Single-lead Handheld Electrocardiograms

for Atrial Fibrillation (AF)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07468123·Enrolling By Invitation

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

31 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting

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A Study of LY4175408 in Participants With Advanced Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY4175408

15 locations incl. Stanford

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07046923·Phase 1·Recruiting

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External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

for Hypoglycemia

1 location in Boston

Sponsor: Joslin Diabetes Center

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07082478·Recruiting

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A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for AML (Acute Myelogenous Leukemia)

13 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 66

Code: NCT06859424·Phase 2·Recruiting

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ACTengine® IMA203 Combined With mRNA-4203

for Cutaneous Melanoma

4 locations incl. San Francisco

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06946225·Phase 1·Recruiting

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ELEVATE High-Risk PCI Pivotal Study

for High-Risk Percutaneous Coronary Intervention (High-risk PCI)

29 locations incl. Scottsdale

Sponsor: Magenta Medical Ltd.

Sex: All·Age: 18 - 88

Code: NCT07001332·Recruiting

Apply to this trial