Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Boston Children's Hospital
Study ID
NCT06721455
Status
Recruiting
Apply to this trial

Conditions

  • Blood Transfusion
  • Heart Surgery
  • Hemolysis

Eligibility Criteria

Sex
ALL
Age
0 Years - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • blood sampling — OTHER
    Discarded blood samples will be taken from routine clinical labs drawn during and after heart surgery.

Study Details

This study aims to learn more about blood management in children undergoing heart surgery, such as the right amounts, and the best blood products, to administer. It also aims to develop a mathematical model that may help researchers better predict and treat patients who need blood transfusions during heart surgery.

Key Dates

Start date
Aug 1, 2025
Status verified
Jan 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Children having heart surgery
    Children under 18 years of age having heart surgery with cardio-pulmonary bypass at Boston Children's Hospital

Primary Outcome Measure

Intraoperative hemolysis during pediatric cardiac cardio-pulmonary bypass (CPB) cases as assessed using the plasma free hemoglobin assessment [ Time Frame: 1 day (during cardio-pulmonary bypass) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02115
Jocelyn Booth, BSN
[email protected]
857-218-4585
Rachel Bernier, MPH
[email protected]
857-218-5348
Koichi Yuki, MD (PRINCIPAL_INVESTIGATOR)

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Boston Children's Hospital· Boston, MA

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