Clinical Trials at University of Kentucky

As of June 2026, 138 paid clinical trials are recruiting at University of Kentucky, located at University of Kentucky Research Foundation, Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508, phone (859) 257-8311 in Lexington, Kentucky. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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138 clinical trials at University of Kentucky

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Impact of Daily Oral Cannabis Doses in Patients With Cancer

for Cancer

1 location in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18+

Code: NCT06601218·Phase 1·Recruiting

Apply to this trial

Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity

for Obesity and Overweight

1 location in Lexington

Sponsor: John Bauer

Sex: All·Age: 12 - 17

Code: NCT06967389·Recruiting

Apply to this trial

Families Moving Together Curriculum

for Physical Activities

1 location in Lexington

Sponsor: Deirdre Dlugonski

Sex: All·Age: 3+

Code: NCT07084064·Recruiting

Apply to this trial

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

for Ankle Sprains

2 locations incl. Lexington

Sponsor: University of Kentucky

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06868316·Recruiting

Apply to this trial

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

21 locations incl. Little Rock

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting

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A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for Lower Extremity Acute Limb Ischemia

31 locations incl. Scottsdale

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT06747117·Recruiting

Apply to this trial

Adaptive Intervention Strategies for HIV PrEP Care in Rural People Who Inject Drugs

for HIV Prevention

4 locations incl. Barbourville

Sponsor: Hilary L Surratt, PhD

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06666309·Enrolling By Invitation

Lead-212 PSV359 Therapy for Patients With Solid Tumors

for Pancreatic Ductal Adenocarcinoma

8 locations incl. Miami

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06710756·Phase 1, Phase 2·Recruiting

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InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery

for Fracture of Hip

1 location in Lexington

Sponsor: Paul E. Matuszewski

Sex: All·Age: 55+

Code: NCT06024304·Recruiting

Apply to this trial

Opioid Drug Interaction Study

for Drug Interactions

1 location in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18 - 55

Code: NCT06757140·Phase 1, Phase 2·Recruiting

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A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for Non-small Cell Lung Cancer

5 locations incl. Lexington

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06731907·Phase 2·Recruiting

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2024 Tirzepatide-Bariatric Surgery

for Obesity and Obesity-related Medical Conditions

Drug: Tirzepatide

1 location in Lexington

Sponsor: Marlene Starr

Sex: All·Age: 18+

Code: NCT06721507·Phase 4·Recruiting

Apply to this trial

Oncology Legal Navigation Study

for Financial Stress

1 location in Lexington

Sponsor: Jean Edward

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07443839·Recruiting

Apply to this trial

MCC-24-GYN-11: Comparison of Nodal Sampling in Endometrial Cancer

for Endometrial Cancer

1 location in Lexington

Sponsor: Rachel Miller

Sex: Female·Age: 18+

Code: NCT06677112·Recruiting

Apply to this trial

Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

for Wound Healing

1 location in Lexington

Sponsor: Janice Hernandez, MD

Sex: All·Age: 18 - 100

Code: NCT07075159·Recruiting

Apply to this trial

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for Multiple System Atrophy

1 location in Lexington

Sponsor: Craig van Horne, MD, PhD

Sex: All·Age: 40 - 75

Code: NCT06683365·Phase 1·Recruiting

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Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

for Degenerative Disc Disease

19 locations incl. Napa

Sponsor: VIVEX Biologics, Inc.

Sex: All·Age: 22 - 85

Code: NCT06778447·Recruiting

Apply to this trial

PT150 Drug for Use in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Lexington

Sponsor: Pop Test Oncology LLC

Sex: All·Age: 21 - 55

Code: NCT06712602·Phase 1·Recruiting

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A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

for Diffuse Large B-Cell Lymphoma

Drug: Rituximab

42 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06717347·Phase 3·Recruiting

Apply to this trial

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

19 locations incl. La Jolla

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06227910·Phase 3·Recruiting

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

Apply to this trial

TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk

for Risk Behavior

2 locations incl. New Haven

Sponsor: University of Kentucky

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05576350·Recruiting

Apply to this trial

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

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FIT Exercise in 30d of ULLS-induced Muscle Disuse

for Muscle Atrophy

1 location in Lexington

Sponsor: Lance Bollinger

Sex: All·Age: 35 - 45·Accepts healthy volunteers

Code: NCT06631053·Recruiting

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

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A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

for Lupus Erythematosus, Systemic

19 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06581198·Phase 2·Recruiting

Apply to this trial

Primary Subtalar Arthrodesis for Calcaneal Fractures

for Calcaneus Fracture

17 locations incl. Orange

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06249126·Recruiting

Apply to this trial

Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage

for Postpartum Hemorrhage

19 locations incl. Birmingham

Sponsor: KOKO Medical Inc.

Sex: Female·Age: 18+

Code: NCT06452355·Recruiting

Apply to this trial

Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace

for Tobacco Use

1 location in Lexington

Sponsor: Mikhail N Koffarnus

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06234722·Enrolling By Invitation

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

for Traumatic Brain Injury

18 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT05826912·Phase 2·Enrolling By Invitation

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

20 locations incl. Los Angeles

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting

Apply to this trial

Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With External Ventricular Drainage

for Subarachnoid Hemorrhage, Aneurysmal

1 location in Lexington

Sponsor: Aaron Cook

Sex: All·Age: 18 - 85

Code: NCT06119061·Phase 4·Recruiting

Apply to this trial

Exercise and Emotional Learning in Posttraumatic Stress Disorder

for PTSD

2 locations incl. Lexington

Sponsor: Christal L Badour

Sex: All·Age: 18 - 64

Code: NCT06127342·Recruiting

Apply to this trial

Preventing Injured Knees From osteoArthritis: Severity Outcomes

for Osteoarthritis, Knee

9 locations incl. Atlanta

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 45

Code: NCT06096259·Phase 2·Recruiting

Apply to this trial

Alternatives to Dental Opioid Prescribing After Tooth Extraction

for Analgesics, Opioid

1 location in Lexington

Sponsor: Douglas Oyler

Sex: All·Age: 12 - 25

Code: NCT06275191·Enrolling By Invitation

Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

10 locations incl. Los Angeles

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting

Apply to this trial

K23- Physical Self Regulation vs Placebo

for Temporomandibular Disorder

1 location in Lexington

Sponsor: Ian Boggero, PhD

Sex: All·Age: 18+

Code: NCT06357702·Recruiting

Apply to this trial

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

for Mild Cognitive Impairment

1 location in Lexington

Sponsor: Julie Pendergast

Sex: Female·Age: 45 - 95

Code: NCT05858008·Recruiting

Apply to this trial