EXoPERT EMERALD Clinical Study
for Breast Cancer
9 locations incl. Long Beach
Sponsor: EXoPERT
Sex: All·Age: 45+·Accepts healthy volunteers
Code: NCT07186296·Recruiting
Lung cancer Clinical Trials in Lexington, KY
As of June 2026, 8 paid clinical trials are recruiting for Lung cancer in Lexington, Kentucky. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Lexington
Filter results
Filter results
8 clinical trials for Lung cancer
·Clear filters·↓ Download CSVA Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
for Advanced Solid Tumor
21 locations incl. Scottsdale
Sponsor: Clasp Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06778863·Phase 1·Recruiting
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
for Non-small Cell Lung Cancer
12 locations incl. La Jolla
Sponsor: Daiichi Sankyo
Sex: All·Age: 18+
Code: NCT06644768·Phase 1, Phase 2·Recruiting
Precision Lung Cancer Survivorship Care Intervention
for Lung Cancer
1 location in Lexington
Sponsor: Jerod L Stapleton, PhD
Sex: All·Age: 18+
Code: NCT05857995·Recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment
for Lung Cancer
1 location in Lexington
Sponsor: Laurie McLouth
Sex: All·Age: 18+
Code: NCT06047301·Recruiting
Empathic Communication Skills (ECS) Training
for Lung Cancer
12 locations incl. Irvine
Sponsor: Memorial Sloan Kettering Cancer Center
Sex: All·Age: 18 - 100·Accepts healthy volunteers
Code: NCT05456841·Recruiting
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
for Pulmonary Nodule, Solitary
22 locations incl. Hartford
Sponsor: Veracyte, Inc.
Sex: All·Age: 29 - 85
Code: NCT06426628·Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
for Brain Cancer
17 locations incl. Duarte
Sponsor: Adela, Inc
Sex: All·Age: 40+·Accepts healthy volunteers
Code: NCT05366881·Recruiting
About research studies in Lexington
Lexington has approximately 508 recruiting research studies across a wide range of therapeutic areas. Kentucky hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Lexington
Researchers run research studies in Lexington, KY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Kentucky | Cancer, Heart Failure, Alcohol Use Disorder | 135 |
| University of Kentucky/Markey Cancer Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 89 |
| Saint Joseph Hospital East | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Anatomic Stage IV Breast Cancer AJCC v8 | 53 |
| Saint Joseph Radiation Oncology Resource Center | Breast Cancer, Prostate Adenocarcinoma, Stage IIIB Lung Cancer AJCC v8 | 43 |
| Baptist Health Lexington | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 39 |
| Saint Joseph Hospital | Prostate Adenocarcinoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 33 |
| University of Kentucky Medical Center | Adenocarcinoma, Pancreatic Ductal, Advanced Solid Tumor, Cachexia | 18 |
| Baptist Health Hamburg | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 11 |
| Kentucky Children's Hospital | Cancer-related Pain, Cardiac Arrest, Cardiopulmonary Arrest | 9 |
| University of Kentucky Chandler Medical Center | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell | 9 |
| Markey Cancer Center | BRAF Gene Mutation, Cancer of Lung, Cancer of the Lung | 7 |
| University of Kentucky Research Foundation | Ankylosing Spondylitis, Autoimmune Diseases, Birdshot Chorioretinitis | 6 |
| Psychopharmacology of Addiction Laboratory | Methamphetamine Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder | 5 |
| The Research Group of Lexington LLC | Obesity, Heart Failure, Cardiovascular Disease | 5 |
| University of Kentucky Hospital | Traumatic Brain Injury, Acute Treatment of Migraine, Atrial Fibrillation | 5 |
| University of Kentucky - Markey Cancer Center | Advanced Liver Cancers, B-Cell Non-Hodgkins Lymphoma, Breast Cancer | 4 |
| University of Kentucky Markey Cancer Center | Advanced Solid Tumor, Bladder Cancer, Breast Cancer | 4 |
| Bluegrass Epilepsy Research | Focal Epilepsy | 3 |
| Bluegrass Epilepsy Research, LLC | Focal Epilepsy, Lennox Gastaut Syndrome, Primary Generalized Tonic-Clonic Seizures | 3 |
| Clinical Trial Site | Cerebral Amyloid Angiopathy, Generalized Myasthenia Gravis, High Cardiovascular Risk | 3 |
| GSK Investigational Site | Colonic Neoplasms, Neoplasms, Colon, Neoplasms, Head and Neck | 3 |
| Research Facility | Carcinoid, Carcinoid Tumor, GEP-NET | 3 |
| University of Kentucky College of Medicine | Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Adolescent Congenital Heart Disease, Candidemia | 3 |
| AMR Clinical | Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight | 2 |
| AMR Lexington | Diabetic Peripheral Neuropathic Pain, RSV Infection | 2 |
Active & Upcoming Studies in Lexington (2026)
Recruiting trials in Lexington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (211 active studies)
- Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma · Phase 2 · National Cancer Institute (NCI)
- A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL) · Phase 1 · Pierluigi Porcu
Neurology & pain (36 active studies)
- Repeated CBD Administration and Cannabis Outcomes · EARLY_Phase 1 · Hannah Harris
- Methadone for Post-operative Spine Surgery · Phase 4 · Brandon Knopp
Cardiovascular (30 active studies)
Diabetes & metabolic (18 active studies)
Mental health & behavior (9 active studies)
- Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD · Phase 4 · Dr. Dean Reeves Clinic
- Health Communications for Adults Smoking Nondaily · Bethany Shorey Fennell, PhD
Pediatric (8 active studies)
- Gamification Effects on the 6-Minute Walk Test in Children · David Toupin
- MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease · Oelisoa Andriankaja
HIV / STI (4 active studies)
- The PROTECT (PrEP Optimization Through Telehealth Care and Treatment) Trial · Hilary L Surratt, PhD
- Adaptive Intervention Strategies for HIV PrEP Care in Rural People Who Inject Drugs · Hilary L Surratt, PhD
Eye & vision (4 active studies)
- Evaluation of a Monofocal Intraocular Lens · Phase 4 · Carl Zeiss Meditec AG
- Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD · Phase 3 · Jaeb Center for Health Research
Vaccines (3 active studies)
- A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant · Phase 2 · GlaxoSmithKline
- Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults · Phase 1 · Clover Biopharmaceuticals USA, LLC
Common conditions studied in Lexington
- Breast Cancer (11 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (9 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Lung Cancer (8 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Stage IV Lung Cancer AJCC v8 (8 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Acute Myeloid Leukemia (7 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Malignant Solid Neoplasm (7 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Lexington
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- AstraZeneca
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Kentucky are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Kentucky research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Lexington. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Lexington
Hipa.ai aggregates every recruiting study in Lexington from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Lexington?
There are approximately 508 recruiting clinical trials in Lexington, Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lexington pay participants?
Most recruiting trials in Lexington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lexington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lexington?
The most common conditions under active study in Lexington include Breast Cancer (11), Heart Failure (9), Lung Cancer (8), Stage IV Lung Cancer AJCC v8 (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lexington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lexington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lexington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lexington?
Recruiting research sites in Lexington include University of Kentucky, University of Kentucky/Markey Cancer Center, Saint Joseph Hospital East, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lexington right now?
The largest active categories in Lexington are Cancer & tumors (211), Neurology & pain (36), Cardiovascular (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Kentucky
Louisville, KY(551)Edgewood, KY(55)Bardstown, KY(48)Corbin, KY(43)Bowling Green, KY(41)London, KY(40)Paducah, KY(38)Owensboro, KY(30)Mount Sterling, KY(29)Shepherdsville, KY(21)Elizabethtown, KY(16)Fort Thomas, KY(8)Crestview Hills, KY(7)Ashland, KY(4)Hazard, KY(4)Morehead, KY(4)Danville, KY(3)Florence, KY(3)Frankfort, KY(3)Murray, KY(3)Nicholasville, KY(3)Pikeville, KY(3)Richmond, KY(3)Madisonville, KY(2)Versailles, KY(2)Barbourville, KY(1)Campbellsville, KY(1)Campton, KY(1)Covington, KY(1)Cynthiana, KY(1)Dyer, KY(1)Elkton, KY(1)Fort Campbell, KY(1)Fort Campbell North, KY(1)Fort Mitchell, KY(1)Greenville, KY(1)Hardinsburg, KY(1)Hartford, KY(1)Henderson, KY(1)Hopkinsville, KY(1)Irvine, KY(1)Jackson, KY(1)Lousiville, KY(1)Manchester, KY(1)Maysville, KY(1)Multiple Locations, KY(1)Newport, KY(1)Pewee Valley, KY(1)Prospect, KY(1)Saint Matthews, KY(1)Whitesburg, KY(1)Winchester, KY(1)