Paid Clinical Trials in Illinois

Illinois has 2,953 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,953 clinical trials

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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

for Chronic Kidney Disease

5 locations incl. Glendale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07024823·Phase 1·Recruiting

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XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

for Locally Advanced Differentiated Thyroid Gland Carcinoma

2 locations incl. Torrance

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06959641·Phase 2·Recruiting

Apply to this trial

Our Voices Matter: Intervention for Depression in Youth

for Depressive Symptoms

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 15 - 20·Accepts healthy volunteers

Code: NCT07216326·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

200 locations incl. Gilbert

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06992427·Phase 3·Recruiting

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Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System

for Behavioral Health

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 13 - 20·Accepts healthy volunteers

Code: NCT06997120·Recruiting

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Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

6 locations incl. Monterey

Sponsor: N-Power Medicine

Sex: All·Age: 18+

Code: NCT07028489·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for Dravet Syndrome

Drug: zorevunersen

31 locations incl. Phoenix

Sponsor: Stoke Therapeutics, Inc

Sex: All·Age: 2 - 17

Code: NCT06872125·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY

for Achievement

1 location in Bloomington

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07011602·Recruiting

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Effects of Effera Human Lactoferrin at One Dose Compared to Placebo on Gut Permeability

for Gut Permeability

1 location in Addison

Sponsor: Helaina Inc.

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07035964·Recruiting

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

32 locations incl. Mobile

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting

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Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for Non-Muscle Invasive Bladder Urothelial Carcinoma

131 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06770582·Phase 2·Recruiting

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Effect of ANNE One-Wellue Device Array Use on Staff Bedside Vital Sign Measurement Activity

for Vital Sign Evaluation

2 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06995742·Recruiting

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Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults

for Spontaneous Breathing Trial in ICU

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07005505·Recruiting

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Mindfulness Walking Intervention to Enhance Resilience (iWalk)

for Neurodegenerative Disease

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07285954·Recruiting

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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for PDAC

18 locations incl. Scottsdale

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06922591·Phase 1, Phase 2·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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PiMZ Longitudinal Cohort (PiMZ Logic)

for Alpha 1-Antitrypsin Deficiency

5 locations incl. Birmingham

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06505603·Recruiting

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A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

7 locations incl. Duarte

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06969430·Phase 1, Phase 2·Recruiting

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

19 locations incl. Phoenix

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting

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A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.

for Osteoarthritis, Knee

40 locations incl. Peoria

Sponsor: Paradigm Biopharmaceuticals Ltd.

Sex: All·Age: 18+

Code: NCT06917404·Phase 3·Recruiting

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

350 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

21 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting

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Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

for Chronic Inducible Urticaria

27 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT06931405·Phase 2·Recruiting

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A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

for Parkinson Disease

15 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 40 - 85

Code: NCT06976268·Phase 2, Phase 3·Recruiting

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Assessment Intravenous Site Events During Outpatient Infusion Procedures With a Wireless Thermal Measurement Device During

for IV Infiltration

1 location in Skokie

Sponsor: Rhaeos, Inc.

Sex: All·Age: 12+

Code: NCT07009405·Recruiting

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Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy

for Iron-deficiency Anemia (IDA)

1 location in Springfield

Sponsor: Southern Illinois University

Sex: Female·Age: 18 - 45

Code: NCT06492512·Phase 4·Recruiting

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Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

21 locations incl. Little Rock

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting

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Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis

for Transthyretin Cardiac Amyloidosis

1 location in Evanston

Sponsor: Idoven 1903 S.L.

Sex: All·Age: 18+

Code: NCT06978660·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

386 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Safety and Tolerability of Eravacycline in Pediatric Patients Aged 8 to 17 With Complicated Intra-abdominal Infections (cIAI)

for Complicated Intra-abdominal Infections (cIAI)

5 locations incl. Los Angeles

Sponsor: Tetraphase Pharmaceuticals, Inc

Sex: All·Age: 8 - 17

Code: NCT06794541·Phase 2·Recruiting

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A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia

for Idiopathic Hypersomnia

Drug: ALKS 2680

32 locations incl. Cullman

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT06843590·Phase 2·Recruiting

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Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria

for Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)

Drug: Remibrutinib

2 locations incl. North Miami Beach

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06865651·Phase 2·Recruiting

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A Study to Understand the Utility of the Force Feedback Instruments in Robotic Procedures Using da Vinci 5 Robot

for Hernia, Inguinal

5 locations incl. Miami

Sponsor: Intuitive Surgical

Sex: All·Age: 22+

Code: NCT06879912·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

for Vulvovaginal Candidiasis (VVC)

10 locations incl. Jacksonville

Sponsor: Coologics, Inc

Sex: Female·Age: 22 - 49

Code: NCT06983041·Recruiting

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Minima Stent System Post- Approval Study (PAS)

for Pulmonary Artery Stenosis

15 locations incl. Los Angeles

Sponsor: Renata Medical

Sex: All·Age: All ages

Code: NCT06828770·Recruiting

Apply to this trial