Clinical Trials at Baylor College of Medicine

As of June 2026, 216 paid clinical trials are recruiting at Baylor College of Medicine, located at 1 BAYLOR PLZ, BCM 286, N1319, HOUSTON, TX 77030-3411, phone (713) 798-8918 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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216 clinical trials at Baylor College of Medicine

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A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management

for Interstitial Cystitis

1 location in Houston

Sponsor: HillMed Inc.

Sex: Female·Age: 18 - 60

Code: NCT05062902·EARLY_Phase 1·Not Yet Recruiting

Multifaceted Intervention to Restore Resilience and Overcome Risk

for Military Sexual Trauma

1 location in Houston

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 18+

Code: NCT06988787·Recruiting

Apply to this trial

Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity

for Depression Disorders

1 location in Houston

Sponsor: Deliberate Solutions Inc.

Sex: All·Age: 18 - 65

Code: NCT06923995·Recruiting

Apply to this trial

VC/VS for Apathy in PD

for Parkinson Disease

1 location in Houston

Sponsor: Nora Vanegas

Sex: All·Age: 40 - 75

Code: NCT06991335·Not Yet Recruiting

Physician-Modified Endografts for Complex Aortic Aneurysms and Thoracoabdominal Aneurysm Repair in High-Risk Patients

for Abdominal Aortic Aneurysms

1 location in Houston

Sponsor: Steven Maximus

Sex: All·Age: 18+

Code: NCT07224230·Recruiting

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

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An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

for Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

9 locations incl. La Jolla

Sponsor: Tisento Therapeutics

Sex: All·Age: All ages

Code: NCT06961344·Phase 2·Enrolling By Invitation

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

17 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting

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The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

for Sickle Cell Disease

14 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 10 - 65

Code: NCT06975865·Phase 3·Recruiting

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

32 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting

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Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation

for Obsessive Compulsive Disorder (OCD)

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 64

Code: NCT06596447·Recruiting

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

25 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting

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Limited Versus Extended Trophic Feeding (LET-FEED) Trial

for Sepsis

6 locations incl. Birmingham

Sponsor: University of Washington

Sex: All·Age: 0 Hours - 36 Hours·Accepts healthy volunteers

Code: NCT06893939·Phase 3·Recruiting

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Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

for Preterm Delivery

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 14+·Accepts healthy volunteers

Code: NCT06980025·Phase 3·Recruiting

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Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

for Obsessive Compulsive Disorder (OCD)

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 7 - 17

Code: NCT07024758·Recruiting

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

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Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

12 locations incl. Scottsdale

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting

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Cooking HEalthy and Facilitating Early Childhood Development: CHEF-ED Study

for Teaching Healthy Cooking Skills to Parents and Their Preschool Children

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06940817·Recruiting

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Alpha Radiation Emitters Device (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

for Pancreatic Cancer

13 locations incl. Gilbert

Sponsor: Alpha Tau Medical LTD.

Sex: All·Age: 18 - 120

Code: NCT06698458·Recruiting

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Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER

for Stage I Colon Cancer

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 80

Code: NCT05870800·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System

for Colorectal Lesion

6 locations incl. Scottsdale

Sponsor: EndoQuest Robotics, Inc.

Sex: All·Age: 22+

Code: NCT06133387·Recruiting

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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Lymphoma

Drug: Glofitamab

16 locations incl. La Jolla

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06624085·Phase 1·Recruiting

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A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

for Chagas Disease

4 locations incl. Sylmar

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 60

Code: NCT06632600·Phase 2·Recruiting

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Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

10 locations incl. Huntsville

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting

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A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis

35 locations incl. Chandler

Sponsor: Boston Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06920043·Phase 2·Recruiting

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A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

30 locations incl. Palo Alto

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting

Apply to this trial

Feasibility and Prospective Study of a Dynamic Traction Device for Use During ESD

for Gastrointestinal Neoplasms

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT06747988·Not Yet Recruiting

Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

for Bradycardia

7 locations incl. Avondale

Sponsor: VDI Technologies

Sex: All·Age: 18+

Code: NCT06641362·Recruiting

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

16 locations incl. Gilbert

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting

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Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

for Rett Syndrome

3 locations incl. Chicago

Sponsor: Rett Syndrome Research Trust

Sex: All·Age: All ages

Code: NCT06338267·Recruiting

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A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

Apply to this trial

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

18 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06722235·Phase 3·Recruiting

Apply to this trial

DETECT-RPC Universal EM Screening

for Elder Abuse

7 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT05958654·Recruiting

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MB-105 in Patients With CD5 Positive T-cell Lymphoma

for Lymphoma, T-Cell

12 locations incl. San Diego

Sponsor: March Biosciences Inc

Sex: All·Age: 18+

Code: NCT06534060·Phase 2·Recruiting

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State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma

for PTSD

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 21 - 64

Code: NCT06888128·Phase 2·Recruiting

Apply to this trial

US National TOP Registry

for Lung Transplant

7 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT06513091·Recruiting

Apply to this trial

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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Deep Brain Stimulation of Treatment-Resistant Bipolar Depression

for Bipolar Depression

4 locations incl. Boston

Sponsor: Wayne Goodman MD

Sex: All·Age: 22 - 64

Code: NCT06599099·Recruiting

Apply to this trial