Behavioral health Clinical Trials in Houston, TX

As of June 2026, 85 paid clinical trials are recruiting for Behavioral health in Houston, Texas. Behavioral health trials span mental-health pharmacotherapy and addiction treatment — testing new agents and therapies for depression, anxiety, opioid use disorder, alcohol use, and tobacco cessation. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

85 clinical trials for Behavioral health

·Clear filters·↓ Download CSV

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

for Major Depressive Disorder

46 locations incl. Phoenix

Sponsor: Cybin IRL Limited

Sex: All·Age: 18 - 85

Code: NCT06564818·Phase 3·Recruiting

Apply to this trial

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics

for Depression

3 locations incl. Oakland

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 80

Code: NCT06526078·Enrolling By Invitation

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

for Autism Spectrum Disorder

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 11 - 17

Code: NCT06537128·Recruiting

Apply to this trial

Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions

for Substance Use

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: Female·Age: 18+

Code: NCT06558825·Recruiting

Apply to this trial

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

24 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting

Apply to this trial

Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)

for Bipolar Disorder

1 location in Houston

Sponsor: Joao L. DeQuevedo

Sex: All·Age: 22 - 85

Code: NCT04080778·Recruiting

Apply to this trial

Cortical rTMS as a Treatment for Depression

for Major Depressive Disorder

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 64

Code: NCT05487911·Enrolling By Invitation

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

for PTSD

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 79

Code: NCT06494319·Recruiting

Apply to this trial

Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)

for Schizophrenia

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 60

Code: NCT06345963·Recruiting

Apply to this trial

Semaglutide for Post-Smoking Cessation Weight Management

for Obesity

Drug: Semaglutide

2 locations incl. Austin

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06173778·Phase 2·Recruiting

Apply to this trial

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

for Depression, Anxiety

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 25+

Code: NCT06200155·Phase 2·Recruiting

Apply to this trial

Reducing Alcohol Exposed Pregnancies

for Alcohol Drinking

1 location in Houston

Sponsor: New York University

Sex: Female·Age: 18+

Code: NCT05766761·Recruiting

Apply to this trial

The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With Psychosis

for Psychosis

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT06194344·Recruiting

Apply to this trial

Telehealth Behavioral Activation for Teens

for Depression

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 - 18

Code: NCT06273995·Recruiting

Apply to this trial

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

for Schizophrenia

47 locations incl. Phoenix

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06229210·Phase 3·Recruiting

Apply to this trial

Pimavanserin for Insomnia in Veterans With PTSD

for Post-traumatic Stress Disorder

1 location in Houston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 64

Code: NCT05441280·Phase 2·Recruiting

Apply to this trial

Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)

for Ovarian Neoplasm

3 locations incl. Dallas

Sponsor: Baylor College of Medicine

Sex: Female·Age: 18+

Code: NCT05752448·Recruiting

Apply to this trial

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

for Posttraumatic Stress Disorder

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05843695·Recruiting

Apply to this trial

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

for Chronic Back Pain

2 locations incl. Dallas

Sponsor: VA Office of Research and Development

Sex: All·Age: 60 - 99

Code: NCT05220202·Recruiting

Apply to this trial

Intracranial Investigation of Neural Circuity Underlying Human Mood

for Depression

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 21 - 70

Code: NCT05871372·Recruiting

Apply to this trial

Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

for Food Insecurity

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05809115·Recruiting

Apply to this trial

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

for Post Traumatic Stress Disorder

12 locations incl. San Diego

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05751473·Recruiting

Apply to this trial

A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking

for Alcohol Abuse

1 location in Houston

Sponsor: University of Houston

Sex: All·Age: 21+

Code: NCT06416059·Recruiting

Apply to this trial

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for Major Depressive Disorder

24 locations incl. Huntsville

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18 - 65

Code: NCT05850689·Phase 3·Recruiting

Apply to this trial

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

for Cognitive Behavioral Therapy

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 7 - 17

Code: NCT05609916·Recruiting

Apply to this trial

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

for Sleep

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05474846·Phase 2, Phase 3·Recruiting

Apply to this trial

Ethnic Microaggressions and Smoking Behaviors Among Latinx Adults

for Smoking

1 location in Houston

Sponsor: University of Houston

Sex: All·Age: 18+

Code: NCT05490927·Recruiting

Apply to this trial

Personalized Feedback Intervention for Latinx Drinkers With Anxiety

for Alcohol Abuse

1 location in Houston

Sponsor: University of Houston

Sex: All·Age: 21 - 75

Code: NCT05246202·Recruiting

Apply to this trial

Pre-exposure Prophylaxis (PrEP) Adherence Intervention for Women with Substance Use Disorders

for Substance Use

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: Female·Age: 18 - 60

Code: NCT06158607·Recruiting

Apply to this trial

Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)

for Smoking Cessation

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 22 - 65

Code: NCT05276050·Recruiting

Apply to this trial

Pilot Study of Virtual Reality Therapy for Students With Anxiety

for Anxiety

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 30

Code: NCT05319509·Recruiting

Apply to this trial

Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing

for Treatment Resistant Depression

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 22 - 70·Accepts healthy volunteers

Code: NCT05418894·Recruiting

Apply to this trial

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

for Schizophrenia

Drug: KarXT

79 locations incl. Phoenix

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 18 - 65

Code: NCT05304767·Phase 3·Recruiting

Apply to this trial

Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans

for PTSD

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05368987·Recruiting

Apply to this trial

Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

for Substance Abuse

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT05489042·Recruiting

Apply to this trial

Manage Emotions to Reduce Aggression (MERA)

for Stress Disorders, Post-Traumatic

2 locations incl. Tampa

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 64

Code: NCT04793776·Recruiting

Apply to this trial

Fear and Avoidance in PTSD Patients

for Post Traumatic Stress Disorder

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT04770584·Recruiting

Apply to this trial

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for Depression

Drug: Cariprazine

69 locations incl. Bentonville

Sponsor: AbbVie

Sex: All·Age: 10 - 17

Code: NCT04777357·Phase 3·Recruiting

Apply to this trial

Young Houston Emergency Opioid Engagement System

for Opioid-use Disorder

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 13 - 17

Code: NCT04811014·Phase 4·Recruiting

Apply to this trial

Neuromodulation and Neurorehabilitation for mTBI

for Mild Traumatic Brain Injury

2 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT03819608·Recruiting

Apply to this trial

Conditions in Behavioral health (Houston, TX)

Depression· 27 PTSD (post-traumatic stress disorder)· 16 Anxiety· 13 Schizophrenia· 12 Tobacco / nicotine use· 7 Substance use disorder· 6 Opioid use disorder· 4 Alcohol use disorder· 4 Bipolar disorder· 3 Obsessive-compulsive disorder (OCD)· 2 ADHD· 1