Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)

Part of paid clinical trials in Houston, Texas.

Sponsor
The University of Texas Health Science Center, Houston
Study ID
NCT05276050
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
22 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • active F8-coil delivered rTMS — DEVICE
    Multiple trains of rTMS in a day, for multiple days.
  • active H-coil delivered rTMS — DEVICE
    Multiple trains of rTMS in a day, for multiple days.

Study Details

Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation. Smoking and brain functional connectivity changes will be assessed at baseline, different stages of rTMS and/or follow-ups.

Key Dates

Start date
Jun 1, 2022
Status verified
Jan 2026
Primary completion
Jul 28, 2026
Completion
Jan 30, 2027

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Study group
    Participants in this group will receive active F8-coil delivered rTMS.
  • Active Comparator: Active control group
    Participants in this group will receive active H-coil delivered rTMS.

Primary Outcome Measure

Resting-state functional connectivity (rsFC) from functional magnetic resonance imaging (fMRI) [ Time Frame: 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas Health Science Center, HoustonHoustonTexas77054
Xiaoming Du, PhD
[email protected]
410-402-6036
Victoria Acosta
[email protected]
713-486-2740

Find similar trials in Houston, TX

By condition
Schizophrenia
By specialty
PsychiatryMental healthBehavioral health
By research site
The University of Texas Health Science Center, Houston· Houston, TX

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